2 SEM ACC W/RAVEN CARDED
12th Edition
ISBN: 9781264439218
Author: Raven
Publisher: MCGRAW-HILL HIGHER EDUCATION
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Textbook Question
Chapter 50, Problem 1DA
How would a high level of HCG present in a urine sample be indicated in this agglutination test?
Expert Solution & Answer
Summary Introduction
To determine: How would a high level of hCG hormone available in a urine sample be represented in the agglutination test.
Introduction: Monoclonal antibodies refer to the antibodies that show specificity for a single epitope alone. In monoclonal antibody preparation, a vertebrate animal, typically a mouse is immunized with an antigen several times and is killed subsequently. The B lymphocytes are combined with cancerous multiple myeloma cells using a procedure described in 1975. These myeloma cells exhibit all the properties of plasma cells, but the immunoglobulins secretion. In a suitable medium, these cells can survive forever and they will multiply indefinitely. Thus, they continuously secrete identical, monoclonal antibodies in large quantities.
Explanation of Solution
The availability of huge amounts of pure monoclonal antibodies has let the development of highly sensitive clinical lab tests. A few pregnancy tests utilize a monoclonal antibody that is produced against the human chorionic gonadotrophin (hCG) hormone. The test utilizes hCG-coated latex particles and it is exposed to an anti-hCG antibody and a urine sample. If the urine sample includes high level of hCG hormone, it will hinder attachment of antibodies to the hCG-coated latex particles and prevent their clumping (agglutination), representing pregnancy depending on the availability of hCG.
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Chapter 50 Solutions
2 SEM ACC W/RAVEN CARDED
Ch. 50.1 - Prob. 1LOCh. 50.1 - Prob. 2LOCh. 50.1 - Prob. 3LOCh. 50.2 - Prob. 1LOCh. 50.2 - Prob. 2LOCh. 50.2 - Prob. 3LOCh. 50.3 - Prob. 1LOCh. 50.3 - Prob. 2LOCh. 50.4 - Explain how antibody diversity is generated.Ch. 50.4 - Prob. 2LO
Ch. 50.4 - Prob. 3LOCh. 50.5 - Define autoimmune diseases.Ch. 50.5 - Prob. 2LOCh. 50.6 - Explain antigenantibody reactions in the ABO blood...Ch. 50.6 - Prob. 2LOCh. 50.6 - Prob. 3LOCh. 50.7 - Prob. 1LOCh. 50.7 - Prob. 2LOCh. 50 - How would a high level of HCG present in a urine...Ch. 50 - What would happen if an NK cell killed a virally...Ch. 50 - Prob. 2IQCh. 50 - Prob. 3IQCh. 50 - Prob. 4IQCh. 50 - Cells that target and kill body cells infected by...Ch. 50 - Structures on invading cells recognized by the...Ch. 50 - Which one of the following acts as the alarm...Ch. 50 - Prob. 4UCh. 50 - Receptors that trigger innate immune responses a....Ch. 50 - Diseases in which the persons immune system no...Ch. 50 - Suppose that a new disease is discovered that...Ch. 50 - You start a new job in a research lab. The lab...Ch. 50 - In comparing T-cell receptors and immunoglobulins...Ch. 50 - If you have type AB blood, which of the following...Ch. 50 - Suppose that you get a paper cut while studying....Ch. 50 - If you wanted to cure allergies by bioengineering...Ch. 50 - Why do we need to be repeatedly vaccinated for...Ch. 50 - Prob. 7ACh. 50 - Suppose you take a job in the marketing department...Ch. 50 - Prob. 2SCh. 50 - Prob. 3SCh. 50 - Toll-like receptors have been found in a wide...
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