HOLES HUMAN ANATOMY AND PHYSIOLOGY
HOLES HUMAN ANATOMY AND PHYSIOLOGY
15th Edition
ISBN: 9781307233995
Author: SHIER
Publisher: MCG
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Chapter 5, Problem 2CA
Summary Introduction

To describe:

The three types of intercellular junctions.

Introduction:

Intercellular junctions are specialized regions of contact between the adjacent cells that function in adhesion and cell communication.

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QUESTION 8 For the following pedigree, assume that the mode of inheritance is X-linked recessive, and that the trait has full penetrance and expressivity and occurs at a very low frequency in the hum population. Using XA for the dominant allele and Xa for the recessive allele, assign genotypes for the following individuals (if it is not possible to figure out the second allele of a genotype, that with an underscore): 2 m 1 2 1 2 4 5 6 7 8 9 IV 1 2 3 5 6 7 8 CO 9 10 12 13 V 1, 2 3 4 5 6 7 8 9 10 11 12 13 a. Il-1: b. 11-2: c. III-3: d. III-4: e. If individuals IV-11 and IV-12 have another child, what is the probability that they will have a boy with the disorder?
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please,show workings ahd solutions calculate the questions showing the solution including variables,unit and equations all the questiosn below using the data a) B1,   b) B2,   c) hybrid rate constant (1) d) hybrid rate constant (2) e) t1/2,dist f) t1/2,elim   g) k10 h) k12 i) k21 j) initial concentration (C0)   k) central compartment volume (V1) l) steady-state volume (Vss)   m) clearance (CL)  AUC (0→10 min) using trapezoidal rule n)  AUC (20→30 min) using trapezoidal rule o) AUCtail (AUC360→∞)   p) total AUC (using short cut method) q) volume from AUC (VAUC)
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