1 SEM ACC W/RAVEN CARDED
1 SEM ACC W/RAVEN CARDED
12th Edition
ISBN: 9781265486297
Author: Raven
Publisher: MCGRAW-HILL HIGHER EDUCATION
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Chapter 48, Problem 1A

In vertebrate hearts, atria contract from the top, and ventricles contract from the bottom. How is this accomplished?

a. Depolarization from the SA node proceeds across the atria from the top; depolarization from the AV node is carried to the bottom of the ventricles before it emanates over ventricular tissue.

b. The depolarization from the SA node is initiated from motor neurons coming down from our brain; depolarization from the AV node is initiated from motor neurons coming up from our spinal cord.

c. Gravity carries the depolarization from the SA node down from the top of the heart; contraction of the diaphragm forces depolarization from the AV node from the bottom up.

d. This statement is false; both contract from the bottom.

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a. What percentage of a drug is eliminated after 4 half-lives? Please round to the nearest percent.  b. What will happen to elimination of the drug in the previous question if the system is saturated? explain and show any math involved
If you wanted to reduce the difference between peak and trough levels that occur with repeated administration of a drug, how would you adjust the dose and dose interval without changing the plateau concentration (plateau is the average of peak and trough levels)? Select your answers for both dose and interval. Hint: It may be helpful to think about this problem using an example such as food. How would you eat if you wanted to maintain very steady hunger/satiety levels without changing your total caloric intake? Options: A. Dose; Increase dose     B. Dose; Decrease dose     C. Dose; Do not change dose     D. Interval; Increase the interval between doses (give the drug less frequently)    E. Interval; Decrease the interval between doses (give the drug more frequently)     F. Interval; Do not change the interval
What percentage of a drug is eliminated after 4 half-lives? Please round to the nearest percent. Show the math
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