CUSTOM BIOLOGY
CUSTOM BIOLOGY
19th Edition
ISBN: 9781323945490
Author: Urry
Publisher: Pearson Custom Publishing
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Chapter 41, Problem 10TYU

SCIENTIFIC INQUIRY In human populations of northern European origin, the disorder called hemochromatosis causes excess iron uptake from food and affects one in 200 adults. Among adults, men are ten times as likely as women to suffer from iron overload. Taking into account the existence of a menstrual cycle in humans, propose a hypothesis that explains this difference.

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. Consider a base substitution mutation that occurred in a DNA sequence that resulted in a change in the encoded protein from the amino acid glutamic acid to aspartic acid. Normally the glutamic acid amino acid is located on the outside of the soluble protein but not near an active site. O-H¨ A. What type of mutation occurred? O-H B. What 2 types of chemical bonds are found in the R-groups of each amino acid? The R groups are shaded. CH2 CH2 CH2 H2N-C-COOH H2N-C-COOH 1 H Glutamic acid H Aspartic acid C. What 2 types of bonds could each R-group of each of these amino acids form with other molecules? D. Consider the chemical properties of the two amino acids and the location of the amino acid in the protein. Explain what effect this mutation will have on this protein's function and why.
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