Explanation Given information: The statement “If the slope of the dose/response curve is large, a small change in the dose will have a large effect on the response”. A dose-response curve plots the intensity of physiological response to a drug as a function of the dose administered. As the dose increases, the intensity of the response increases, so a dose-response function is increasing. The intensity of the response is generally scaled as a percentage of the maximum response. The curve cannot go above the maximum response (or 100%), so the curve levels off at a horizontal asymptote. Dose-response curves are generally concave up for low doses and concave down for high doses. A dose-response curve can be modeled by a logistic function with the independent variable being the dose of the drug, not time. A dose-response curve shows the amount of drug needed to produce the desired effect, as well as the maximum effect attainable and the dose required to obtain it...

6th Edition

ISBN: 9781119399353

Author: DA

Publisher: JOHN WILEY+SONS,INC.-CONSIGNMENT

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Chapter 4, Problem 66SYU

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Whether the statement is true or false.

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Chapter 4, Problem 65SYU

Chapter 4, Problem 67SYU

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u, v and w are three coplanar vectors: ⚫ w has a magnitude of 10 and points along the positive x-axis ⚫ v has a magnitude of 3 and makes an angle of 58 degrees to the positive x- axis ⚫ u has a magnitude of 5 and makes an angle of 119 degrees to the positive x- axis ⚫ vector v is located in between u and w a) Draw a diagram of the three vectors placed tail-to-tail at the origin of an x-y plane. b) If possible, find w × (ū+v) Support your answer mathematically or a with a written explanation. c) If possible, find v. (ū⋅w) Support your answer mathematically or a with a written explanation. d) If possible, find u. (vxw) Support your answer mathematically or a with a written explanation. Note: in this question you can work with the vectors in geometric form or convert them to algebraic vectors.

Question 3 (6 points) u, v and w are three coplanar vectors: ⚫ w has a magnitude of 10 and points along the positive x-axis ⚫ v has a magnitude of 3 and makes an angle of 58 degrees to the positive x- axis ⚫ u has a magnitude of 5 and makes an angle of 119 degrees to the positive x- axis ⚫ vector v is located in between u and w a) Draw a diagram of the three vectors placed tail-to-tail at the origin of an x-y plane. b) If possible, find w × (u + v) Support your answer mathematically or a with a written explanation. c) If possible, find v. (ū⋅ w) Support your answer mathematically or a with a written explanation. d) If possible, find u (v × w) Support your answer mathematically or a with a written explanation. Note: in this question you can work with the vectors in geometric form or convert them to algebraic vectors.

Chapter 4 Solutions

EBK APPLIED CALCULUS, ENHANCED ETEXT

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To indicate: Whether the statement is true or false.

Solution Summary: The author explains how the dose-response curve plots the intensity of physiological response to a drug. The slope of the curve gives information about the therapeutic safety margin.