VANDER'S HUMAN PHY W/ CONNECT & PROCT +
VANDER'S HUMAN PHY W/ CONNECT & PROCT +
15th Edition
ISBN: 9781265160920
Author: WIDMAIER
Publisher: MCG
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Chapter 4, Problem 4RC
Summary Introduction

Introduction: The movements of ions and molecules across the cell membrane are regulated by a set of transport mechanisms that are collectively termed as membrane transport mechanisms.

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22. Which of the following mutant proteins is expected to have a dominant negative effect when over-   expressed in normal cells?   a. mutant PI3-kinase that lacks the SH2 domain but retains the kinase function   b. mutant Grb2 protein that cannot bind to RTK   c. mutant RTK that lacks the extracellular domain   d. mutant PDK that has the PH domain but lost the kinase function   e. all of the above
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