Biological Science (7th Edition)
7th Edition
ISBN: 9780134678320
Author: Scott Freeman, Kim Quillin, Lizabeth Allison, Michael Black, Greg Podgorski, Emily Taylor, Jeff Carmichael
Publisher: PEARSON
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Which of the following is correct regarding nucleotide structure?
Removal of the ribose-phosphate groups from thymidylic acid or thymidylate yields thymidine
Removal of the ribose-phosphate groups from cytidine yields cytosine
Removal of the phosphate group from guanylic acid or guanylate yields guanine.
Removal of the phosphate group from adenylate or adenylic acid yields adenosine
Match the following terms with their correct definition.
The structure of double-standed DNA
Hold the base pairs together and make up the rungs of the DNA double helix
One strand of nucleotides running in the opposite direction of the other strand
Consists of a phosphate, a sugar backbone, and a nitrogen base
A-T and C-G base pairs
Five-carbon sugar found in DNA
Answer Complementary base pairs Answer Double helix Answer Antiparallel Answer Nucleotide Answer Hydrogen bonds Answer Deoxyribose sugar
Spot the difference between the chemical structures of DNA & RNA and state the said difference in a short paragraph. Please refer in the attached picture for the answer.
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- Draw a stylized diagram of double-stranded DNA. Use a pentagon for sugar, a circle for phosphate and a square for bases. Label each base A, T, C or G. Show two pairs of nucleotides connected via hydrogen bonds (use all 4 letters). Show the polarity of each strand and clearly indicate the number of hydrogen bonds in each pair of nucleotides. Draw a solid-line circle around a nucleotide. Draw a dashed-line circle around a nucleoside. Indicate a phosphodiester bond using an arrow.arrow_forwardA nucleotide is the monomeric building block of the polymer of DNA. To better understand the characteristics of DNA, it is important to understand how the monomers join to form the polymer. Use the following diagram of DNA (and the diagram of a nucleotide in the PowerPoint presentation) to label the listed features: 3' and 5' ends, nucleotide, phosphate group, sugar group, phosphodiester bond, nitrogenous base (pyrimidine and purine), and hydrogen bonds. NHZ NH2 HN OH₂N NH₂ 5. Looking at the polymer, why is a DNA considered antiparallel? 6. Why are the ends of DNA strands named 3' or 5'? 7. How do A:T interactions differ compared to G:C interactions? How does this affect stability of the bond pairs? 8. During gel electrophoresis, to which electrode (+ or -) does DNA migrate? Why?arrow_forwardList the DNA bases that will complementary base pair with the following sequence: A-G-C-T-A-C-Garrow_forward
- Match the following with the correct nucleic acid. (mRNA, tRNA, rRNA, or All RNA) 1. This molecule is complementary to DNA. 2. This molecule is part of translation. 3. This molecule is part of the ribosome. 4. This molecule contains anticodons. 5. This molecule is esponsible for bringing amino acids to the ribosome. 6. DNA is used as a template to create this type of RNA molecule. 7. This molecule is part of transcription. 8. This molecule contains codons.arrow_forwardDetermine what amino acid will be formed from the given DNA strand below: 3’ T A C A T G C C G A A T 5’ Note: Prepare the partner strand of this DNA. Discuss how will replication happen by mentioning the enzyme needed then transcribe to form mRNA. Discuss what will happen to mRNA, then translate, mentioning the anticodon to be used. Look at the genetic code to know what amino acid will become part of the polypeptide chain. 1. Partner DNA strand 2. the mRNA strand 3. the tRNA 4. the formed amino acidsarrow_forwardWhich of the following does NOT describe DNA as it occurs in Eukaryotic cells. CHOOSE ALL THAT APPLY: 1. nitrogenous bases of opposite strands are paired through covalent bonds 2. base pairs are stacked 3.4 A (0.34 nm) apart 3. the two strands of one double helix are complementary 4. two long polynucleotide chains 5. there are 20 base pairs per each turn of a double helix 6. adenine pairs with thymine of the neighboring nucleotide in a single DNA strand 7. bases face outside of the double helix 8. consecutive nucleotides of a single DNA strand are linked by hydrogen bonds 9. here are A-T and G-C pairs in DNA double helix 10. sugar-phosphate backbone of a single DNA strand is formed by linking deoxyribose units and phosphate groups through phosphodiester bonds 11. the two strands of one helix are antiparallel 12.double helix 13. the larger major groove alternates with the smaller minor groove along the length of the double stranded DNA I tried 2,3,4,9,10,11,12,13 together and got it…arrow_forward
- Hydrolysis of the N-glycosyl bond between deoxyribose and a purine base in DNA creates an apurinic (AP) site. An AP site is more thermodynamically destabilizing to a DNA molecule than is a mismatched base pair. Examine the structure of an AP site. H₂N HN N O™ -O-P-O-CH₂ Guanine H₂N N HN Select the chemical consequences that could contribute to DNA instability at AP sites. H H 1₂0/ H fewer hydrogen bonds between the unpaired pyrimidine base and water disruption of the base-stacking interactions decreased interaction between the mutated DNA strand and histones increased ability of the deoxyribose ring to open without the attachment of the purine base H H Guanosine residue (in DNA) O™ -O-P-O-CH₂ O H H H O Apurinic residue H OH Harrow_forwardChoose the CORRECT components of a nucleoside. a pentose sugar bonded with a hexose sugar a base bonded to a sugar and one or more phosphoryl groups a sugar bonded to a lipid molecule a base bonded to a sugar a base bonded to a sugar and an alcohol residuearrow_forwardWhich of the following combinations is nucleotide molecule? The nitrogenous base uracil bonded to ribose and phosphate complemented with the addition of a water molecule A nucleoside resulting from the dehydration reaction between two phosphates, glycerol, and an unsaturated fatty acid. The DNA backbone consisting of three phosphate groups, a 5-carbon nitrogenous base, and a nitrogen-containing sugar residue An ATP molecule is formed by combining adenine, ribose, and three inorganic phosphate groupsarrow_forward
- Select the phrases that accurately describe properties of the most common form of the DNA double helix. DNA contains equal amounts of adenine and thymine and equal amounts of cytosine and guanine. The nitrogenous bases are exposed to the solvent, whereas the sugar-phosphate backbone of each nucleotide strand is in the interior of the double helix. The phosphodiester bonds between nucleotide residues run in opposite directions in the two strands. Base pairs have a spacing of 3.4 Å. A helical turn consists of about 3.4 base pairs.arrow_forwardDNA has unique properties that allow it to accurately retain genetic information, even after multiple rounds of replication. One aspect of DNA that allows it to accurately store genetic information is the base pairing from Chargaff's first rule of the four nucleotide bases. If the A content of a DNA molecule is 18%, what are the percentages of the remaining bases? T = G = C = % % %arrow_forwardConsider the structure and function of DNA. Which of the following statements is TRUE? Because DNA contains carbohydrates, it provides structural support to the cells. The phosphodiester bonds that stabilize the association of the two strands are easily broken and reformed. If the sequence of one DNA strand is known, then the sequence of the other strand can be determined. Because DNA is made of phosphate groups that are ionized, it could easily pass through a cell membrane.arrow_forward
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