Concept explainers
In Drosophila, the autosomal recessive brown eye color mutation displays interactions with both the X-linked recessive vermilion mutation and the autosomal recessive scarlet mutation. Flies homozygous for brown and simultaneously hemizygous or homozygous for vermilion have white eyes. Flies simultaneously homozygous for both the brown and scarlet mutations also have white eyes. Predict the F1 and F2 progeny of crossing the following true-breeding parents:
a. vermilion females × brown males
b. brown females × vermilion males
c. scarlet females × brown males
d. brown females × scarlet males

To determine:
The F1 and F2 progeny from the cross between vermilion females and brown males
Introduction:
The genes are the sequence of nucleotides that are present on the chromosomes and encode for a specific protein that plays a crucial role in the functioning of the different processes in an organism. The gene is located at specific gene loci and can be structural or regulatory in nature.
Explanation of Solution
The allele for vermillion trait can be expressed as (XVXV) and the allele for brown trait is (EbEb). The F1 progeny from cross between vermilion females and brown males will be as follows:
Gametes | XV | XV |
Eb | XV Eb | XV Eb |
Eb | XV Eb | XV Eb |
The F2 progeny will be as follows:
Gametes | XV | Eb |
XV | XV XV | XV Eb |
Eb | XV Eb | Xb Eb |

To determine:
The F1 and F2 progeny from the cross between brown females and vermilion males
Introduction:
The genotype is the genetic constitution of the organism while the phenotype is the external characters visible in an organism. The alleles are the contrasting forms of a gene and one of them is dominant and other is recessive
Explanation of Solution
The vermillion males can be expressed as (XVY) and the brown females can be expressed as (Eb Eb). The progeny from the cross of vermilion males and brown females will be as follows:
Gametes | Eb | Eb |
XV | XV Eb | XV Xb |
Y | Eb Y | Eb Y |
The progeny obtained from the F2 cross will be
Gametes | Eb | Y |
XV | XV Eb | XVY |
Eb | Eb Eb | Eb Y |

To determine:
The F1 and F2 progeny from the cross between brown females and vermilion males
Introduction:
The dominant allele masks the expression of the recessive allele. Therefore the dominant allele is expressed in homozygous and heterozygous genotype while the recessive phenotype is only expressed under homozygous condition.
Explanation of Solution
The scarlet females can be expressed through alleles (ESES) and the brown males are expressed as (EbEb). The progeny from the cross of brown males and scarlet females will be as follows:
Gametes | Eb | Eb |
Es | Eb Es | Eb Es |
Es | Eb Es | Eb Es |
The progeny obtained from the F2 cross will be
Gametes | Es | Eb |
Eb | Eb Es | Eb Eb |
Es | Es Es | Eb Es |

To determine:
The F1 and F2 progeny from the cross between brown females and scarlet males
Introduction:
Fertilization is the process by which the male gamete, sperm, fertilize with the female gamete, ovary. The process brings about the fusion of two haploid pronuclei into a diploid zygote.
Explanation of Solution
The brown females can be seen as (EbEb) and scarlet males are represented as (ESES). The progeny from the cross of brown females and scarlet males will be as follows:
Gametes | Eb | Eb |
Es | Eb Es | Eb Es |
Es | Eb Es | Eb Es |
The progeny obtained from the F2 cross will be
Gametes | Es | Eb |
Eb | Eb Es | Eb Eb |
Es | Es Es | Eb Es |
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Chapter 4 Solutions
ND STONY BROOK UNIVERSITY LOOSELEAF GENETICS: FROM GENES TO GENOMES
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