Biochemistry
Biochemistry
6th Edition
ISBN: 9781305577206
Author: Reginald H. Garrett, Charles M. Grisham
Publisher: Cengage Learning
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Chapter 4, Problem 1P

Answers to all problems are at the end of this book. Detailed solutions are available in the Student Solutions Manual, Study Guide, and Problems Book.

  1. Drawing Fischer Projection Formulas for Amino Acids Without consulting chapter figures, draw Fischer projection formulas for glycine, aspartate, leucine, isoleucine, methionine, and threonine.

Expert Solution & Answer
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Interpretation Introduction

Interpretation:

The Fischer projection formulas for the following amino acids should be drawn.

Glycine, Aspartate, Leucine, Isoleucine, Methionine and Threonine.

Concept Introduction:

Fisher projection formula is the method used to predict a stereo formula within two dimensions without hampering the stereochemical information.

Explanation of Solution

All amino acids contain α - carbon atom attached to an amino group, hydrogen bond, and a distinguishing R group.

The R group of glycine is hydrogen.

  Biochemistry, Chapter 4, Problem 1P , additional homework tip  1

Glycine:

The R group of aspartates is a -CH2COOH.

  Biochemistry, Chapter 4, Problem 1P , additional homework tip  2

The R group of leucine is an isobutyl group.

  Biochemistry, Chapter 4, Problem 1P , additional homework tip  3

The R group of isoleucine is a sec-butyl group.

  Biochemistry, Chapter 4, Problem 1P , additional homework tip  4

The R group of methionine is a thioether of methyl and ethyl groups.

  Biochemistry, Chapter 4, Problem 1P , additional homework tip  5

The R group of threonine contains another chiral carbon attached to methyl and a hydroxyl group.

  Biochemistry, Chapter 4, Problem 1P , additional homework tip  6

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