EBK BIOLOGY: CONCEPTS AND APPLICATIONS
EBK BIOLOGY: CONCEPTS AND APPLICATIONS
9th Edition
ISBN: 9780100478657
Author: STARR
Publisher: YUZU
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Chapter 4, Problem 13SQ
Summary Introduction

Introduction:

Many cells secrete an extracellular matrix (ECM) which is a complex mixture of molecules that includes polysaccharides and fibrous proteins. The composition and function of ECM varies by the type of cell that secretes it.

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22. Which of the following mutant proteins is expected to have a dominant negative effect when over-   expressed in normal cells?   a. mutant PI3-kinase that lacks the SH2 domain but retains the kinase function   b. mutant Grb2 protein that cannot bind to RTK   c. mutant RTK that lacks the extracellular domain   d. mutant PDK that has the PH domain but lost the kinase function   e. all of the above
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