Prescott's Microbiology
11th Edition
ISBN: 9781260211887
Author: WILLEY, Sandman, Wood
Publisher: McGraw Hill
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Chapter 38.3, Problem 1MI
Summary Introduction
To determine: To determine the function of intergrase and its role in latency.
Introduction: Acquired immune deficiency syndrome (AIDS) is one of the significant health problems prevalent in today’s population. The causative agent of AIDS is a human immunodeficiency virus (HIV). HIV virion is 110 nm in diameter having various enzymes and two copies of the RNA genome.
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The following table is from Kumar et. al. Highly Selective Dopamine D3 Receptor (DR) Antagonists and Partial Agonists Based on Eticlopride and the D3R Crystal Structure: New Leads for Opioid Dependence Treatment. J. Med Chem 2016.
The following figure is from Caterina et al. The capsaicin receptor: a heat activated ion channel in the
pain pathway. Nature, 1997. Black boxes indicate capsaicin, white circles indicate resinferatoxin.
You are a chef in a fancy new science-themed restaurant. You have a recipe that calls for 1 teaspoon of resinferatoxin, but you feel uncomfortable serving foods with "toxins" in them. How much capsaicin could you substitute instead?
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Chapter 38 Solutions
Prescott's Microbiology
Ch. 38.1 - Prob. 1MICh. 38.1 - Why is it thought that the characteristic rash is...Ch. 38.1 - Prob. 3MICh. 38.1 - Prob. 1CCCh. 38.1 - Prob. 2CCCh. 38.1 - Prob. 3CCCh. 38.1 - Prob. 4CCCh. 38.1 - Prob. 5CCCh. 38.1 - Prob. 6CCCh. 38.1 - Prob. 7CC
Ch. 38.3 - Prob. 1MICh. 38.3 - Prob. 2MICh. 38.3 - Prob. 1CCCh. 38.3 - Prob. 2CCCh. 38.3 - Prob. 3CCCh. 38.3 - Prob. 4CCCh. 38.3 - Prob. 5CCCh. 38.3 - Prob. 6CCCh. 38.4 - Prob. 1CCCh. 38.4 - Prob. 2CCCh. 38.4 - Prob. 3CCCh. 38.4 - Prob. 4CCCh. 38.5 - Prob. 1MICh. 38.5 - Prob. 1CCCh. 38.5 - Prob. 2CCCh. 38.5 - Prob. 3CCCh. 38.6 - How are prions different from viruses? How are...Ch. 38.6 - In what way are spongiform encephalopathies...Ch. 38 - Prob. 1RCCh. 38 - Prob. 2RCCh. 38 - Prob. 3RCCh. 38 - Prob. 1ALCh. 38 - Prob. 2ALCh. 38 - Prob. 3ALCh. 38 - Prob. 4ALCh. 38 - Prob. 5ALCh. 38 - Prob. 6AL
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- 1. Match each vocabulary term to its best descriptor A. affinity B. efficacy C. inert D. mimic E. how drugs move through body F. how drugs bind Kd Bmax Agonist Antagonist Pharmacokinetics Pharmacodynamicsarrow_forward50 mg dose of a drug is given orally to a patient. The bioavailability of the drug is 0.2. What is the volume of distribution of the drug if the plasma concentration is 1 mg/L? Be sure to provide units.arrow_forwardDetermine Kd and Bmax from the following Scatchard plot. Make sure to include units.arrow_forward
- Choose a catecholamine neurotransmitter and describe/draw the components of the synapse important for its signaling including synthesis, packaging into vesicles, receptors, transporters/degradative enzymes. Describe 2 drugs that can act on this system.arrow_forwardThe following figure is from Caterina et al. The capsaicin receptor: a heat activated ion channel in the pain pathway. Nature, 1997. Black boxes indicate capsaicin, white circles indicate resinferatoxin. a) Which has a higher potency? b) Which is has a higher efficacy? c) What is the approximate Kd of capsaicin in uM? (you can round to the nearest power of 10)arrow_forwardWhat is the rate-limiting-step for serotonin synthesis?arrow_forward
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