Chapter 3.6, Problem 23P

Q9: Explain why compound I is protonated on O while compound II is protonated on N. NH2 DD I II NH2

Complete the following reaction by identifying the principle organic product of the reaction

Denote the dipole for the indicated bonds in the following molecules. ✓ H3C CH3 B F-CCl3 Br-Cl H3C —Si(CH3)3 CH3 OH HO HO H HO OH vitamin C

(a) What is the hybridization of the carbon in the methyl cation (CH3*) and in the methyl anion (CH3)? (b) What is the approximate H-C-H bond angle in the methyl cation and in the methyl anion?

10:16 ☑ Vo)) Vo) 4G LTE 76% Complete the following reaction by identifying the principle organic product of the reaction. HO OH ↑ CH2N2 OH ? ○ A. 01 N₂H2C OH ОН B. HO OCH3 OH ○ C. HO OH ŎCH₂N2 ○ D. H3CO OH он Quiz navigation 1 2 3 4 5 11 12 Next page 10 6 7 8 9 10

Which one of the following statements explain why protecting groups are referred to as “a necessary evil in organic synthesis”?   Question 12Select one or more:   A. They increase the length and cost of the synthesis       B. Every synthesis employs protecting groups       C. Protecting group have no role to play in a synthesis     D. They minimize the formation of side products

Which of the following attributes is a key advantage of the chiral auxiliary approach over the chiral pool approach in asymmetric synthesis?   Question 10Select one:   A. Chiral auxiliaries are cheaper than chiral pool substrates     B. Chiral auxiliary can be recovered and recycled unlike chiral pool substrates.     C. The use of chiral auxiliaries provide enantiopure products, while chiral pool reactions are only enantioselective       D. The chiral auxiliaries are naturally occurring and do not require synthesis

In the following molecule, indicate the hybridization and shape of the indicated atoms. CH3 CH3 H3C HO: CI:

Which of the following are TRUE about linear syntheses?   Question 7Select one:   A. They are easier to execute     B. They are the most efficient strategy for all syntheses       C. They are generally shorter than convergent syntheses       D. They are less versatile compared to convergent syntheses