
Histamine acts on the _____, causing redness and swelling.
a. white blood cells
b. cells lining blood vessels
c. outermost layer of skin
d. red blood cells

Introduction:
Inflammation is caused in the blood cells due to the entry of the pathogens. It causes redness and swelling in the blood vessels. It is released from the mast cells at the site of injury. It causes the blood vessels to dilate and increases the membrane permeability. The white blood cells reach the site of infection by squeezing through the spaces in the capillaries and blood vessels.
Answer to Problem 2MCQ
Correct answer:
Histamine acts on the cells lining blood vessels, causing redness and inflammation. Therefore, option b. is correct.
Explanation of Solution
Reason for the correct statement:
The injury to the blood vessels causes the release of the histamine from the mast cells. It is a chemical mediator of the damage of the cell membrane.
Option b. is given as “cells lining blood vessels”.
As, “Histamine acts on the cells lining blood vessels causing redness and swelling”, is the right answer.
Hence, option b. is correct.
Reasons for the incorrect statements:
Option a. is given as “white blood cells”.
White blood cells reach the site of infection after an injury but histamine is released during redness and inflammation of the blood vessels. So, it is a wrong answer.
Option c. is given as “outermost layer of skin”.
The outermost layer of the skin is called as epidermis which gets destroyed during infection but histamine is released from the mast cells during redness and swelling. So, it is a wrong answer.
Option d. is given as “red blood cells”.
Red blood cells are present at the site of injury but histamine is released from the site of redness and swelling. So, it is a wrong answer.
Hence, options a., c., and d. are incorrect.
Inflammation causes redness and swelling at the site of infection due to the infection caused by the microorganisms leading to the release of histamine from the mast cells.
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