Concept explainers
In the plasma membrane, _____ form(s) the lipid bilayer, __________determine(s) the fluid nature of the membrane, and __________
mainly determine(s) the function of the membrane.
a. phospholipids, cholesterol, proteins
b. phospholipids, proteins, cholesterol
c proteins, cholesterol, phospholipids
d. cholesterol, phospholipids, proteins
c. cholesterol, proteins, phospholipids

Introduction:
The proteins are made of amino acids. The amino acids are of 20 types that combine in a varied manner to form proteins. The amino acids join together by peptide bonds. Proteins act as major substrates and reactants for the metabolic pathways. All the enzymes in the body that are crucial for the biochemical reactions are proteins.
Answer to Problem 1RAC
The correct answer is option (a) phospholipids, cholesterol, proteins.
Explanation of Solution
Explanation/justification for the correct answer:
Option (a) phospholipids, cholesterol, proteins. The phospholipids form the bilayer of the cell membrane, and the cholesterol promotes fluidity of the membrane to allow the movement of cytoplasm inside and the protein play a different role in the function of the cell membrane. So, the correct answer is option (a).
Explanation for incorrect answer:
Option (b) phospholipids, proteins, cholesterol. Phospholipids make up the lipid bilayer, and the cholesterol promotes fluidity to steroid and alcohol in its structure, and so it does not provide the function to the membrane. So, this is an incorrect option.
Option (c) proteins, cholesterol, phospholipids. The phospholipids form the bilayer that is integrated with proteins and protein do not form the bilayer of the plasma membrane. So, this is an incorrect answer.
Option (d) cholesterol, phospholipids, and proteins. Cholesterol does not make the bilayer; the bilayer is made up of phospholipids and embedded proteins. So, this is an incorrect answer.
Option (e) cholesterol, proteins, phospholipids. Phospholipids only make up the structure of the cellular membrane and do not determine the function of the membrane; this function is carried out by protein that is intrinsic and extrinsic. So, this is an incorrect answer.
Phospholipids form the bilayer which is made up of two lipid layers making a sandwich with protein embedded in between two layers; cholesterol provides fluidity and proteins help to determine the function of the membrane. Hence, the correct answer is option (a) phospholipids, cholesterol, proteins.
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