SEELEY'S ANATOMY+PHYSIOLOGY
12th Edition
ISBN: 9781260172195
Author: VanPutte
Publisher: RENT MCG
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Textbook Question
Chapter 3, Problem 10RAC
Which of these statements concerning the symport of glucose into cells is true!
a. The sodium-potassium exchange pump moves Na+ into cells.
b. The concentration of Na+ outside cells is less than inside cells.
c. A carrier protein moves Na+ into cells and glucose out of cells.
d. The concentration of glucose can be greater inside cells than outside cells.
e. As Na+ are actively transported into the cell, glucose is carried along.
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Digoxin: Intravenous Bolus - Two Compartment Model
Drug
Digoxin
Route:
IV Bolus
Dose:
0.750 mg
Plasma Concentration Time Profile
Beta
Alpha
Time (hrs)
Conc (ng/ml)
LN
(ng/ml)
LN
(ng/ml)
LN
0.00
#NUM!
#NUM!
#NUM!
0.10
12.290
2.509
#NUM!
#NUMI
0.60
6.975
1.942
#NUM!
#NUMI
1.00
4.649
1.537
#NUM!
#NUMI
2.00
2.201
0.789
#NUM!
#NUM!
3.00
1.536
0.429
#NUM!
#NUM!
4.00
1.342
0.294
#NUM!
#NUM!
5.00
1.273
0.241
#NUM!
#NUMI
6.00
1.238
0.213
#NUM!
#NUM!
7.00
1.212
0.192
#NUM!
#NUM!
8.00
1.188
0.172
#NUMI
#NUM!
9.00
1.165
0.153
#NUM!
#NUMI
10.00
1.143
0.134
#NUMI
#NUM!
11.00
1.122
0.115
#NUM!
12.00
1.101
0.096
#NUMI
13.00
1.080
0.077
#NUMI
16.00
1.020
0.020
#NUMI
24.00
0.876
-0.132
#NUMI
Pharmacokinetic Parameters
Parameter
Value
Alpha
B
Beta
Units
ng/ml
hr-1
ng/ml
hr-1
CO
ng/ml
H.C
AUC
ng x hr/ml
Vc
Vbeta
Vss
C
L/hr
TK (alpha)
hr
TX (beta)
days
5+
F3
F4
F5
0+
F6
F7
%
6
95
14
#3
29
&
t
F8
F9
FW
EW
Linuron, a derivative of urea, is used as an herbicide. Linuron serum levels were measured in 4Kg
rabbits following a bolus IV injection of 10mg/kg.
Time (minutes)
Serum Linuron Levels (ug/ml)
following IV dose
10
15.48
20
8.60
30
5.90
45
3.78
60
2.42
90
1.49
120
0.93
180
0.60
240
0.41
300
0.29
360
0.22
Analyze this data and perform the necessary calculations to determine the following pharmacokinetic
parameters from the IV data: (5 points per parameter, 24 parameters/variables ■ 120 points
possible). You do NOT need to submit graphs or data tables.
Give the terminal regression line equation and R or R² value:
Give the x axis (name and units, if any) of the terminal line:
Give the y axis (name and units, if any) of the terminal line:
Give the residual regression line equation and R or R² value:
Give the x axis (name and units, if any) of the residual line:
Give the y axis (name and units, if any) of the residual line:
Chapter 3 Solutions
SEELEY'S ANATOMY+PHYSIOLOGY
Ch. 3.1 - What parts are common to most cells?Ch. 3.1 - Explain the four characteristic functions of the...Ch. 3.2 - Which cell features can be seen with a light...Ch. 3.3 - Explain five functions of the plasma membrane.Ch. 3.3 - Prob. 5AYPCh. 3.3 - Prob. 6AYPCh. 3.3 - What are the main chemical components of the...Ch. 3.4 - Prob. 8AYPCh. 3.4 - Summarize the characteristics of the fluid-mosaic...Ch. 3.4 - Prob. 10AYP
Ch. 3.5 - Prob. 11AYPCh. 3.5 - Prob. 12AYPCh. 3.5 - What are the three classes of transport proteins?Ch. 3.5 - Describe specificity, competition, and saturation...Ch. 3.5 - Prob. 15AYPCh. 3.5 - Prob. 16AYPCh. 3.5 - Prob. 17AYPCh. 3.5 - Prob. 18AYPCh. 3.5 - Prob. 19AYPCh. 3.5 - Prob. 20AYPCh. 3.6 - Explain why the plasma membrane is selectively...Ch. 3.6 - Prob. 22AYPCh. 3.6 - Describe how the amount of solute in a solvent...Ch. 3.6 - How is the rate of diffusion affected by an...Ch. 3.6 - Prob. 25AYPCh. 3.6 - Compare isosmotic, hyperosmotic, and hyposmotic...Ch. 3.6 - Prob. 27AYPCh. 3.6 - Prob. 28AYPCh. 3.6 - What is secondary active transport? Describe how...Ch. 3.6 - Prob. 30AYPCh. 3.6 - Prob. 31AYPCh. 3.6 - Prob. 32AYPCh. 3.6 - Describe and give examples of exocytosis.Ch. 3.7 - Prob. 34AYPCh. 3.7 - Prob. 35AYPCh. 3.7 - List and describe the functions of microtubules,...Ch. 3.7 - What are cytoplasmic inclusions? Give several...Ch. 3.8 - Define organelles. Are oil orgonelles found in oil...Ch. 3.8 - Describe the structure of the nucleus and the...Ch. 3.8 - Prob. 40AYPCh. 3.8 - Prob. 41AYPCh. 3.8 - Prob. 42AYPCh. 3.8 - What molecules combine to form ribosomes? Where...Ch. 3.8 - Prob. 44AYPCh. 3.8 - Prob. 45AYPCh. 3.8 - What are the functions of the rough endoplasmic...Ch. 3.8 - Prob. 47AYPCh. 3.8 - Relate the structure and function of the Golgi...Ch. 3.8 - Prob. 49AYPCh. 3.8 - Prob. 50AYPCh. 3.8 - Prob. 51AYPCh. 3.8 - Prob. 52AYPCh. 3.8 - What are the structure and function of...Ch. 3.8 - Describe the structure of a mitochondrion. How...Ch. 3.8 - What enzymes are found on the cristae? In the...Ch. 3.8 - What is the centrosome? Relate the structure of...Ch. 3.8 - What are spindle fibers? Explain the relationship...Ch. 3.8 - Prob. 58AYPCh. 3.8 - Prob. 59AYPCh. 3.9 - Prob. 60AYPCh. 3.9 - Prob. 61AYPCh. 3.9 - Prob. 62AYPCh. 3.9 - Prob. 63AYPCh. 3.9 - Prob. 64AYPCh. 3.9 - Prob. 65AYPCh. 3.9 - Prob. 66AYPCh. 3.9 - Place the steps of translation in sequence. In...Ch. 3.9 - Prob. 68AYPCh. 3.9 - State two ways the cell controls what part of DNA...Ch. 3.10 - Describe the cell’s activities during the G1, S....Ch. 3.10 - Prob. 71AYPCh. 3.10 - Prob. 72AYPCh. 3.10 - Prob. 73AYPCh. 3.10 - Differentiate among chromot in, chromcitids, and...Ch. 3.10 - Prob. 75AYPCh. 3.10 - Prob. 76AYPCh. 3.10 - Prob. 77AYPCh. 3.11 - Prob. 78AYPCh. 3 - In the plasma membrane, _____ form(s) the lipid...Ch. 3 - Which of the following functioning proteins are...Ch. 3 - In general, lipid-soluble molecules diffuse...Ch. 3 - Small pieces of matter, and even whole cells, can...Ch. 3 - The rate of diffusion increases if the a....Ch. 3 - Concerning the process of diffusion, at...Ch. 3 - Prob. 7RACCh. 3 - Prob. 8RACCh. 3 - Which of these statements about facilitated...Ch. 3 - Which of these statements concerning the symport...Ch. 3 - A white blood cell ingests solid particles by...Ch. 3 - Given these characteristics: (1) requires energy...Ch. 3 - Cytoplasm is found a. in the nucleus. b. outside...Ch. 3 - Which of these elements of the cytoskeleton is...Ch. 3 - A large structure, normally visible in the nucleus...Ch. 3 - A cell that synthesizes large amounts of protein...Ch. 3 - Which of thes organelles produces large amounts of...Ch. 3 - Prob. 18RACCh. 3 - A portion of an mRNA molecule that determines one...Ch. 3 - In which of these organelles is m RNA synthesized?...Ch. 3 - During the cell cycle, DNA replication occurs...Ch. 3 - Given the following activities: Repair Growht...Ch. 3 - Apoptosis Is a programmed cell death. Removes...Ch. 3 - Prob. 1CTCh. 3 - Prob. 2CTCh. 3 - Prob. 3CTCh. 3 - Prob. 4CTCh. 3 - Luke started a training program at the beginning...Ch. 3 - Prob. 6CT
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