Loose Leaf For Integrated Principles Of Zoology
Loose Leaf For Integrated Principles Of Zoology
18th Edition
ISBN: 9781260411140
Author: Cleveland P Hickman Jr. Emeritus, Susan L. Keen, David J Eisenhour Professor PhD, Allan Larson, Helen I'Anson Associate Professor of Biology
Publisher: McGraw-Hill Education
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Chapter 3, Problem 1FFT
Summary Introduction

To propose: The reasons why the CFTR channel may not be present in the plasma membrane of some cystic fibrosis patients or may not function correctly in other patients.

Introduction: Cystic fibrosis is the inherited genetic autosomal recessive disorder. It is caused by the mutation in the gene that codes for transmembrane protein channel and that allows for the movement of chloride ions. As a result of this, the body produces thick and sticky mucus that obstructs the lungs.

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Imagine that you are a clinical geneticist. Your colleague is an oncologist who wants your help explaining the basics of genetics to their patient, who will be undergoing genetic testing in the coming weeks for possible acute myeloid leukemia (AML) induced by the radiation she had several years ago for breast cancer. Write a 1,050- to 1,225-word memo to your colleague. Include the following in your memo: An explanation of the molecular structure of DNA and RNA, highlighting both similarities and differences  A description of the processes of transcription and translation An explanation of the differences between leading and lagging strands and how the DNA is replicated in each strand Reponses to the following common questions patients might ask about this type of genetic testing and genetic disorder: Does AML run in families? What genes are tested for?
Respond to the following in a minimum of 175 words: What are some potential consequences that could result if the processes of replication, transcription, and translation don’t function correctly? Provide an example of how you might explain these consequences in terms that patients might understand.
answer questions 1-10
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