Biochemistry
Biochemistry
6th Edition
ISBN: 9781337359573
Author: Reginald H. Garrett; Charles M. Grisham
Publisher: Cengage Learning US
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Chapter 28, Problem 8P

Human Genome Replication Rate Assume DNA replication proceeds at a rate of 100 base pairs per second in human cells and origins of replication occur every 300 kbp. Assume also that human DNA polymerases are highly processive and only two molecules of DNA polymerase arc needed per replication fork. How long would it take to replicate the entire diploid human genome? How many molecules of DNA polymerase does each cell need to carry out this task?

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12. When glutamic acid is heated to 180°C., it loses a molecule of water to form a lactam. The bond that creates the lactam is an amide bond that forms between the amino nitrogen and the carbon of the side chain -COOH group. What is the most reasonable structure for this lactam? (NOTE: The structure of glutamic acid is shown in Question 1.) COOH COOH ا کچھ جو کچھ C D COOH B COOH E COOH
10. Which one of the following compounds is the major organic product of the series of reactions shown here? Ph A OH Ph B CO₂Et Br -H Ν ΚΑ CO₂Et 1. NaOEt 1. NaOH, H₂O 2. H3O+ 2. PhCH2CH2Br 3. heat NH2 Ph OH NH2 0 OH Ph OH NH2 Ph D NH2 E OH
1. What is the isoelectric point of glutamic acid? (Glutamic acid has pKa1 2.10, pKa2 4.07, pKaз 9.47) A) pH 2.1 D) pH 6.8 B) pH 3.1 C) pH 4.1 E) pH 9.5 HO NH2 Glutamic acid (shown without charges) OH
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