ORGANIC CHEMISTRY LL BUNDLE
ORGANIC CHEMISTRY LL BUNDLE
4th Edition
ISBN: 9781119761112
Author: Klein
Publisher: WILEY
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Chapter 25, Problem 56PP
Interpretation Introduction

Interpretation:

Preparation of valine by using Strecker synthesis needs to be shown.

Concept introduction:

Strecker synthesis is a process in which the aldehyde reacts with ammonium chloride and alkali cyanide to form α -aminonitrile.  The formed α -aminonitrile is undergoes hydrolysis to give the respective amino acids.  The general scheme can be shown as,

ORGANIC CHEMISTRY LL BUNDLE, Chapter 25, Problem 56PP

Steps involved in Strecker synthesis are,

  • Protonation of carbonyl
  • Nucleophilic attack of ammonia to form imine
  • Attack of cyanide to form α -aminonitrile
  • Hydrolysis to give α -aminoacid

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Chapter 25 Solutions

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