Biology: Concepts and Investigations
Biology: Concepts and Investigations
5th Edition
ISBN: 9781260259049
Author: Hoefnagels
Publisher: MCG
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Chapter 25, Problem 4MCQ
Summary Introduction

Introduction :

The building blocks of the brain and central nervous systems are neurons or nerve cells. Receiving sensory information, sending motor orders to muscles, and sending electric impulses to gland cells are the primary functions of cells.

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You aim to test the hypothesis that the Tbx4 and Tbx5 genes inhibit each other's expression during limb development. With access to chicken embryos and viruses capable of overexpressing Tbx4 and Tbx5, describe an experiment to investigate whether these genes suppress each other's expression in the limb buds. What results would you expect if they do repress each other? What results would you expect if they do not repress each other?
You decide to delete Fgf4 and Fgf8 specifically in the limb bud. Explain why you would not knock out these genes in the entire embryo instead.
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Biology: Concepts and Investigations

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