BIOCHEMISTRY II >CUSTOM<
BIOCHEMISTRY II >CUSTOM<
17th Edition
ISBN: 9781337449014
Author: GARRETT
Publisher: CENGAGE C
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Chapter 25, Problem 16P

A Deficiency on 3-Phosphogtycerate Dehydrogenase Can Affect Amino Acid Metabolism Although serine is a nonessential amino acid, serine deficiency syndrome has been observed in humans. One such form of the syndrome is traceable to a deficiency in 3-phosphoglycerate dehydrogenase (see Figure 25.31). Individuals with this syndrome not only arc serine-deficient but also arc impaired in their ability to synthesize another common ammo acid, as well as a class of lipids. Describe why.

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7. Which one is the major organic product obtained from the following reaction? CHO COOH CH₂OH CHO COOH H- -OH H₂ H- OH H- -OH H- -OH Ni HO -H HO -H HO- -H HO- H HO- H H- -OH H- -OH H- -OH H -OH H- -OH H- -OH H- -OH H- -OH H- -OH H -OH CH₂OH CH₂OH CH₂OH CH₂OH COOH A B C D
4. The compound on the right is- B) a ketopentose C) an aldohexose A) an aldopentose D) a ketohexose E) a ketoheptose OH OH CH2OH OH
12. When glutamic acid is heated to 180°C., it loses a molecule of water to form a lactam. The bond that creates the lactam is an amide bond that forms between the amino nitrogen and the carbon of the side chain -COOH group. What is the most reasonable structure for this lactam? (NOTE: The structure of glutamic acid is shown in Question 1.) COOH COOH ا کچھ جو کچھ C D COOH B COOH E COOH
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