EP CONNECT ONLINE ACCESS FOR BIOLOGY
20th Edition
ISBN: 9781260494655
Author: Raven
Publisher: MCG COURSE
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Chapter 24, Problem 2S
One of the common misconceptions about sequencing projects (especially the high-profile Human Genome Project) is that creating a complete road map of the DNA will lead directly to cures for genetically based diseases. Given the percentage similarity m DNA between humans and chimps, is this simplistic view justified? Explain.
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What are some of the technical challenges of cloning a mammoth? Check all that are true
Ancient mammoth DNA has degraded so it is hard to know the complete genome sequence
Mammoth gestation time is likely too short to allowing cloning
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Chapter 24 Solutions
EP CONNECT ONLINE ACCESS FOR BIOLOGY
Ch. 24.1 - Prob. 1LOCh. 24.1 - Prob. 2LOCh. 24.1 - Prob. 3LOCh. 24.2 - Prob. 1LOCh. 24.2 - Prob. 2LOCh. 24.2 - Prob. 3LOCh. 24.2 - Explain why genome size and genome number do not...Ch. 24.3 - Define the terms segmental duplication, genome...Ch. 24.3 - Prob. 2LOCh. 24.4 - Prob. 1LO
Ch. 24.4 - Prob. 2LOCh. 24.5 - Prob. 1LOCh. 24.5 - Prob. 2LOCh. 24.5 - Prob. 3LOCh. 24 - Prob. 1DACh. 24 - Prob. 1IQCh. 24 - Prob. 2IQCh. 24 - Prob. 3IQCh. 24 - Humans and pufferfish diverged from a common...Ch. 24 - Prob. 2UCh. 24 - Prob. 3UCh. 24 - Homologous genes in distantly related organisms...Ch. 24 - All of the following are believed to contribute to...Ch. 24 - What is the fate of most duplicated genes? a. Gene...Ch. 24 - Chimp and human DNA whole-genome sequences differ...Ch. 24 - Prob. 2ACh. 24 - Analyze the conclusion that the Medicago...Ch. 24 - Analyze why an herbicide that targets the...Ch. 24 - The FOX2 gene is associated with speech in human....Ch. 24 - One of the common misconceptions about sequencing...Ch. 24 - How does horizontal gene transfer (HGT) complicate...
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- Increasingly, whole-genome sequencing of individuals is being done to help identify and treat medical conditions. Genome sequencing invariably identifies a number of variations, some common and some rare, that might be clinically relevant. For example, suppose a person had their genome sequenced to help determine their risk for cardiovascular disease and, just by chance, the sequence revealed that they carry one or more variants that predispose them to cancer or Alzheimer disease. Does the sequencing laboratory or physician have an obligation to report this finding, which was not the purpose of the sequencing and which the patient did not request? What about reporting variants for which no or limited information can be provided about their clinical significance? Does the answer to this question differ for sequencing done on children?arrow_forwardThe idea behind PCR-based diagnostics is that a very small number of microbial genomes in a patient sample can be multiplied by PCR and more easily detected by the clinical team managing the patient’s care. Also, genetic-based diagnostics are very useful for viral infections because we don’t have biochemical tests, etc. to distinguish one virus from another (remember, viruses are metabolically inactive). However, a lot of work goes into the development of these tests. For instance, PCR requires primers that are complementary to the viral genome that is being copied. If primers are complementary to the target genome, what must scientists know to design primers that bind to the viral genome to be copied? (I mean this to be a general question; don’t look up the details of designing primers)arrow_forwardBioinformatics is an interdisciplinary field that integrates knowledge of computer science with mathematics and statistics to solve biological questions. Many bioinformatics tools for gene prediction, homology modelling and such are available free online. (1) What does BLAST stand for? (ii) Explain the function of BLAST.arrow_forward
- Please help.arrow_forwardWhich goals of the Human Genome Project do you think are themost important? Why? Discuss the types of ethical problems thatmight arise as a result of identifying all of our genes.arrow_forwardWhich of the following is FALSE of functional genomics? Select ALL that apply. RNA seq is a functional genomics approach CHIP seq is a functional genomics approach It seeks to elucidate the roles of genetic sequences of a given species Was invented by Carey Mullis Seeks to edit the DNA sequence of the organism Artificial selection is a functional genomics approacharrow_forward
- "Whole-Genome Sequencing Is Widely Used for Sequencing and Assembling Entire Genomes". Explain this ?arrow_forwardWhy a multiple sequence alignment is needed for researchers? What inferences can be derived from this kind of sequence alignments? Explain two extreme cases that are non-informative for the multiple sequence alignment.arrow_forwarda) Write a short description of why someone would choose to write about wolves vs. dogs. Make an argument for why this topic is interesting. b) Write a short description of why someone would choose this paper below of comparative analysis of the blood transcriptomes between wolves. How does this paper relate to wolves vs. dogs? c) How can you tell that this is a primary research paper and not a review article?arrow_forward
- Much of the human genome consists of repetitious DNA. Describe the difference between microsatellite and minisatel lite DNA. How is this repetitious DNA useful for identifying individuals by the technique of DNA fingerprinting?arrow_forwardPick one (1) of the five (5) principles developed by the Ethics Committee for the Human Genome Organization that must be considered when the global community is confronted by new technology. Why do you feel that principle is MOST important.arrow_forwardConsider the following four DNA sequences taken from the a homologous gene from four different organisms. The bases are in groups of 10 for ease of interpretation. ACTGCGAGGT ACTGCGAGTT ACTTCGAGTT GCCATGTCAС GCCGTGAGAC GCCATGTGAC AGTACTGACG Organism 1 Organism 2 Organism 3 Organism 4 GCATCAGGAТ GCACCAGGAT GCATCAGGAT ACGCAGAAAT AATTCTGAGA AGTACTGACA AGTTCTGAGA ACGCAGAAAT ATGCAGAAAT GCTGCGAGTT GCACCAGGAT GCCATGACÁC ACGCGAAAAT a. For each pair of organisms determine the genetic distance between them. The genetic distance is simply the percentage difference between the two genes. Since each sequence is 50 base bases long, the genetic distance will be 2x the number of base differences. For example, if two sequences are identical except for one base, the genetic distance is 2%. b. List the genetic distances in the table below for each pair of organisms. Organism 1 Organism 2 Organism 3 Organism 4 Organism 4 Organism 3 Organism 2 Organism 1 c. Draw a phylogenetic tree of these 4 organisms, in…arrow_forward
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