The heptapeptide sequence of amino acids, on the basis of the information provided, is to be deduced. Concept introduction: On treating a polypeptide with 2,4-dinitrofluorobenzene in basic solution, the free amino group of the N-terminal gives a nucleophilic aromatic substitution reaction, which, on hydrolysis, gives a mixture of amino acids in which the N-terminal amino acid is labeled with a 2,4-dinitrophenyl group. The C-terminal residues are identified through the carboxypeptidase enzymes. These enzymes catalyze the hydrolysis of the amide bond of the amino acid residue containing a free liberating carboxylic acid group.

Question

Want to see the full answer?

Answer 1

Question

Definition Definition Class of organic compounds that contain a carboxyl group ( - COOH ) and has a general formula R - COOH or R - CO 2 H , where R refers to the alkyl, alkenyl, aryl, or other groups. They can undergo different chemical reactions, such as acid-base reactions, esterification, and oxidation. These are essential components of living organisms, playing important roles in metabolic processes, signaling, and as pharmaceuticals.

Chapter 24, Problem 23P

Interpretation Introduction

Interpretation:

The heptapeptide sequence of amino acids, on the basis of the information provided, is to be deduced.

Concept introduction:

On treating a polypeptide with 2,4-dinitrofluorobenzene in basic solution, the free amino group of the N-terminal gives a nucleophilic aromatic substitution reaction, which, on hydrolysis, gives a mixture of amino acids in which the N-terminal amino acid is labeled with a 2,4-dinitrophenyl group. The C-terminal residues are identified through the carboxypeptidase enzymes. These enzymes catalyze the hydrolysis of the amide bond of the amino acid residue containing a free liberating carboxylic acid group.

Expert Solution & Answer

Want to see the full answer?

Check out a sample textbook solution

See solution

Students have asked these similar questions

4 Part C Give the IUPAC name and a common name for the following ether: Spell out the full names of the compound in the indicated order separated by a comma.

Try: Draw possible resonance contributing structures for the following organic species: CH3CH2NO2 [CH2CHCH2] [CH2CHCHO] [CH2CHCH2] [CH2CHNH2]

Complete the following synthesis. (d). H+ ง с

Answer 2

Question

Definition Definition Class of organic compounds that contain a carboxyl group ( - COOH ) and has a general formula R - COOH or R - CO 2 H , where R refers to the alkyl, alkenyl, aryl, or other groups. They can undergo different chemical reactions, such as acid-base reactions, esterification, and oxidation. These are essential components of living organisms, playing important roles in metabolic processes, signaling, and as pharmaceuticals.

Chapter 24, Problem 23P

Interpretation Introduction

Interpretation:

The heptapeptide sequence of amino acids, on the basis of the information provided, is to be deduced.

Concept introduction:

On treating a polypeptide with 2,4-dinitrofluorobenzene in basic solution, the free amino group of the N-terminal gives a nucleophilic aromatic substitution reaction, which, on hydrolysis, gives a mixture of amino acids in which the N-terminal amino acid is labeled with a 2,4-dinitrophenyl group. The C-terminal residues are identified through the carboxypeptidase enzymes. These enzymes catalyze the hydrolysis of the amide bond of the amino acid residue containing a free liberating carboxylic acid group.

Expert Solution & Answer

Want to see the full answer?

Check out a sample textbook solution

See solution

Answer 3

Question

Definition Definition Class of organic compounds that contain a carboxyl group ( - COOH ) and has a general formula R - COOH or R - CO 2 H , where R refers to the alkyl, alkenyl, aryl, or other groups. They can undergo different chemical reactions, such as acid-base reactions, esterification, and oxidation. These are essential components of living organisms, playing important roles in metabolic processes, signaling, and as pharmaceuticals.

Chapter 24, Problem 23P

Interpretation Introduction

Interpretation:

The heptapeptide sequence of amino acids, on the basis of the information provided, is to be deduced.

Concept introduction:

On treating a polypeptide with 2,4-dinitrofluorobenzene in basic solution, the free amino group of the N-terminal gives a nucleophilic aromatic substitution reaction, which, on hydrolysis, gives a mixture of amino acids in which the N-terminal amino acid is labeled with a 2,4-dinitrophenyl group. The C-terminal residues are identified through the carboxypeptidase enzymes. These enzymes catalyze the hydrolysis of the amide bond of the amino acid residue containing a free liberating carboxylic acid group.

Expert Solution & Answer

Want to see the full answer?

Check out a sample textbook solution

See solution

Answer 4

Question

Definition Definition Class of organic compounds that contain a carboxyl group ( - COOH ) and has a general formula R - COOH or R - CO 2 H , where R refers to the alkyl, alkenyl, aryl, or other groups. They can undergo different chemical reactions, such as acid-base reactions, esterification, and oxidation. These are essential components of living organisms, playing important roles in metabolic processes, signaling, and as pharmaceuticals.

Chapter 24, Problem 23P

Interpretation Introduction