Chapter 24, Problem 12P

One of your colleagues has designed a new transdermal patch to deliver insulin through the skin to diabetic patients in a controlled way, eliminating the need for painful injections. She hascollected the following data on the mass flux of insulin being delivered through the patch (and skin) as a function of time:

Flux, Mg/cm2/h	Time, h	Flux, Mg/cm2/h	Time, h
15	0	8	5
14	1	5	10
12	2	2.5	15
11	3	2	20
9	4	1	24

Remember that mass flux is flow rate through an area or $\left(1/A\right)dm/dt$, Provide your best possible estimate for the amount of drug delivered through the skin in 24 hours using a $12{\text{ cm}}^2$ patch.