The structures of the amine and dialdehyde that react with dimethylacetonedicarboxylate in a Mannich reaction to yield cocaine are to be given. Concept introduction: The first step in a Mannich reaction involves a reaction between an aldehyde and a secondary amine, to yield an iminium ion intermediate along with water. In the second step the iminium ion intermediate reacts with cyclohexanone to yield the product. To give: The structures of the amine and dialdehyde that react with dimethylacetonedicarboxylate in a Mannich reaction to yield cocaine.

Question

Draw the Lewis structure of the SO3-O(CH3)2 complex shown in the bottom right of slide 2in lecture 3-3 (“Me” means a CH3 group) – include all valence electron pairs and formal charges.From this structure, should the complex be a stable molecule? Explain.

Answer 1

Question

Definition Definition Organic compounds that have a carbonyl group, C=O, as their functional group. The carbonyl group in aldehydes is placed at the end of the molecular structure, which means the C=O is attached to one hydrogen atom and an alkyl group or a benzene ring. Just like all the other homologous series in organic chemistry, the naming of aldehydes uses the suffix “-al”. The general molecular formula is C n H 2n O.

Chapter 23.SE, Problem 46MP

Interpretation Introduction

Interpretation:

The structures of the amine and dialdehyde that react with dimethylacetonedicarboxylate in a Mannich reaction to yield cocaine are to be given.

Concept introduction:

The first step in a Mannich reaction involves a reaction between an aldehyde and a secondary amine, to yield an iminium ion intermediate along with water. In the second step the iminium ion intermediate reacts with cyclohexanone to yield the product.

To give:

The structures of the amine and dialdehyde that react with dimethylacetonedicarboxylate in a Mannich reaction to yield cocaine.

Expert Solution & Answer

Trending nowThis is a popular solution!

See solution

Check out sample textbook solution

Students have asked these similar questions

Draw the Lewis structure of the SO3-O(CH3)2 complex shown in the bottom right of slide 2in lecture 3-3 (“Me” means a CH3 group) – include all valence electron pairs and formal charges.From this structure, should the complex be a stable molecule? Explain.

Predict all organic product(s), including stereoisomers when applicable.

Q5: Propose a reasonable synthesis for the following decalin derivative. using only decalin and alkanes of 3 or fewer carbons. Decalin H3C HO க CH3

Answer 2

Question

Definition Definition Organic compounds that have a carbonyl group, C=O, as their functional group. The carbonyl group in aldehydes is placed at the end of the molecular structure, which means the C=O is attached to one hydrogen atom and an alkyl group or a benzene ring. Just like all the other homologous series in organic chemistry, the naming of aldehydes uses the suffix “-al”. The general molecular formula is C n H 2n O.

Chapter 23.SE, Problem 46MP

Interpretation Introduction

Interpretation:

The structures of the amine and dialdehyde that react with dimethylacetonedicarboxylate in a Mannich reaction to yield cocaine are to be given.

Concept introduction:

The first step in a Mannich reaction involves a reaction between an aldehyde and a secondary amine, to yield an iminium ion intermediate along with water. In the second step the iminium ion intermediate reacts with cyclohexanone to yield the product.

To give:

The structures of the amine and dialdehyde that react with dimethylacetonedicarboxylate in a Mannich reaction to yield cocaine.

Expert Solution & Answer

Trending nowThis is a popular solution!

See solution

Check out sample textbook solution

Answer 3

Question

Definition Definition Organic compounds that have a carbonyl group, C=O, as their functional group. The carbonyl group in aldehydes is placed at the end of the molecular structure, which means the C=O is attached to one hydrogen atom and an alkyl group or a benzene ring. Just like all the other homologous series in organic chemistry, the naming of aldehydes uses the suffix “-al”. The general molecular formula is C n H 2n O.

Chapter 23.SE, Problem 46MP

Interpretation Introduction

Interpretation:

The structures of the amine and dialdehyde that react with dimethylacetonedicarboxylate in a Mannich reaction to yield cocaine are to be given.

Concept introduction:

The first step in a Mannich reaction involves a reaction between an aldehyde and a secondary amine, to yield an iminium ion intermediate along with water. In the second step the iminium ion intermediate reacts with cyclohexanone to yield the product.

To give:

The structures of the amine and dialdehyde that react with dimethylacetonedicarboxylate in a Mannich reaction to yield cocaine.

Expert Solution & Answer

Trending nowThis is a popular solution!

See solution

Check out sample textbook solution

Answer 4

Question

Definition Definition Organic compounds that have a carbonyl group, C=O, as their functional group. The carbonyl group in aldehydes is placed at the end of the molecular structure, which means the C=O is attached to one hydrogen atom and an alkyl group or a benzene ring. Just like all the other homologous series in organic chemistry, the naming of aldehydes uses the suffix “-al”. The general molecular formula is C n H 2n O.

Chapter 23.SE, Problem 46MP

Interpretation Introduction