Chapter 23.8, Problem 24PTS

(a)

Interpretation Introduction

Interpretation: Via Heck reaction, the coupling partners that can be used to prepare the given compound have to be identified.

Concept Introduction:

Heck reaction:

It is the coupling reaction between an aryl, vinyl or benzyl halide and an alkene in the presence of an appropriate $\text{Pd}$ catalyst.

Examples:

  

The halogen atom will be mostly iodine because it is the least electronegative atom so that it can readily leave as leaving group.

The coupling partners for the given compound can be found using the retro synthetic approach as shown here:

Example:

  

(b)

Interpretation Introduction

Interpretation: Via Heck reaction, the coupling partners that can be used to prepare the given compound have to be identified.

Concept Introduction:

Heck reaction:

It is the coupling reaction between an aryl, vinyl or benzyl halide and an alkene in the presence of an appropriate $\text{Pd}$ catalyst.

Examples:

  

The halogen atom will be mostly iodine because it is the least electronegative atom so that it can readily leave as leaving group.

The coupling partners for the given compound can be found using the retro synthetic approach as shown here:

Example:

  

(c)

Interpretation Introduction

Interpretation: Via Heck reaction, the coupling partners that can be used to prepare the given compound have to be identified.

Concept Introduction:

Heck reaction:

It is the coupling reaction between an aryl, vinyl or benzyl halide and an alkene in the presence of an appropriate $\text{Pd}$ catalyst.

Examples:

  

The halogen atom will be mostly iodine because it is the least electronegative atom so that it can readily leave as leaving group.

The coupling partners for the given compound can be found using the retro synthetic approach as shown here:

Example:

(d)

Interpretation Introduction

Interpretation: Via Heck reaction, the coupling partners that can be used to prepare the given compound have to be identified.

Concept Introduction:

Heck reaction:

It is the coupling reaction between an aryl, vinyl or benzyl halide and an alkene in the presence of an appropriate $\text{Pd}$ catalyst.

Examples:

  

The halogen atom will be mostly iodine because it is the least electronegative atom so that it can readily leave as leaving group.

The coupling partners for the given compound can be found using the retro synthetic approach as shown here:

Example:

  

(e)

Interpretation Introduction

Interpretation: Via Heck reaction, the coupling partners that can be used to prepare the given compound have to be identified.

Concept Introduction:

Heck reaction:

It is the coupling reaction between an aryl, vinyl or benzyl halide and an alkene in the presence of an appropriate $\text{Pd}$ catalyst.

Examples:

  

The halogen atom will be mostly iodine because it is the least electronegative atom so that it can readily leave as leaving group.

The coupling partners for the given compound can be found using the retro synthetic approach as shown here:

Example:

  

(f)

Interpretation Introduction

Interpretation: Via Heck reaction, the coupling partners that can be used to prepare the given compound have to be identified.

Concept Introduction:

Heck reaction:

It is the coupling reaction between an aryl, vinyl or benzyl halide and an alkene in the presence of an appropriate $\text{Pd}$ catalyst.

Examples:

  

The halogen atom will be mostly iodine because it is the least electronegative atom so that it can readily leave as leaving group.

The coupling partners for the given compound can be found using the retro synthetic approach as shown here:

Example: