Chapter 23, Problem 3EQ

Summary Introduction

To review:

The technique and procedure of in-situ hybridization (ISH).

Introduction:

The cytogenetic mapping of the genes or chromosomal DNA (deoxyribonucleic acid) can be performed by ISH. In this technique, chromosomes are fixed within the cells on a slide and are treated with a fluorescently labeled probe, which is detected microscopically.