Human Biology Lab
15th Edition
ISBN: 9781308566672
Author: McGraw-Hill Education
Publisher: Mcgraw-Hill
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Textbook Question
Chapter 23, Problem 2TC
In studying recent fossils of the genus Homo, such as Cro-Magnon, biologists have determined that modern humans have not undergone much biological evolution in the past 50,000 years. Rather, cultural anthropologists argue that cultural evolution has been far more important than biological evolution in the recent history of modern humans. What do they mean by this? Support your argument with some examples.
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Digoxin: Intravenous Bolus - Two Compartment Model
Drug
Digoxin
Route:
IV Bolus
Dose:
0.750 mg
Plasma Concentration Time Profile
Beta
Alpha
Time (hrs)
Conc (ng/ml)
LN
(ng/ml)
LN
(ng/ml)
LN
0.00
#NUM!
#NUM!
#NUM!
0.10
12.290
2.509
#NUM!
#NUMI
0.60
6.975
1.942
#NUM!
#NUMI
1.00
4.649
1.537
#NUM!
#NUMI
2.00
2.201
0.789
#NUM!
#NUM!
3.00
1.536
0.429
#NUM!
#NUM!
4.00
1.342
0.294
#NUM!
#NUM!
5.00
1.273
0.241
#NUM!
#NUMI
6.00
1.238
0.213
#NUM!
#NUM!
7.00
1.212
0.192
#NUM!
#NUM!
8.00
1.188
0.172
#NUMI
#NUM!
9.00
1.165
0.153
#NUM!
#NUMI
10.00
1.143
0.134
#NUMI
#NUM!
11.00
1.122
0.115
#NUM!
12.00
1.101
0.096
#NUMI
13.00
1.080
0.077
#NUMI
16.00
1.020
0.020
#NUMI
24.00
0.876
-0.132
#NUMI
Pharmacokinetic Parameters
Parameter
Value
Alpha
B
Beta
Units
ng/ml
hr-1
ng/ml
hr-1
CO
ng/ml
H.C
AUC
ng x hr/ml
Vc
Vbeta
Vss
C
L/hr
TK (alpha)
hr
TX (beta)
days
5+
F3
F4
F5
0+
F6
F7
%
6
95
14
#3
29
&
t
F8
F9
FW
EW
Linuron, a derivative of urea, is used as an herbicide. Linuron serum levels were measured in 4Kg
rabbits following a bolus IV injection of 10mg/kg.
Time (minutes)
Serum Linuron Levels (ug/ml)
following IV dose
10
15.48
20
8.60
30
5.90
45
3.78
60
2.42
90
1.49
120
0.93
180
0.60
240
0.41
300
0.29
360
0.22
Analyze this data and perform the necessary calculations to determine the following pharmacokinetic
parameters from the IV data: (5 points per parameter, 24 parameters/variables ■ 120 points
possible). You do NOT need to submit graphs or data tables.
Give the terminal regression line equation and R or R² value:
Give the x axis (name and units, if any) of the terminal line:
Give the y axis (name and units, if any) of the terminal line:
Give the residual regression line equation and R or R² value:
Give the x axis (name and units, if any) of the residual line:
Give the y axis (name and units, if any) of the residual line:
Chapter 23 Solutions
Human Biology Lab
Ch. 23.1 - Describe the conditions of the early Earth’s...Ch. 23.1 - Prob. 2LOCh. 23.1 - Prob. 3LOCh. 23.1 - Prob. 4LOCh. 23.2 - Prob. 1LOCh. 23.2 - Prob. 2LOCh. 23.2 - Discuss how the fossil record, biogeography, and...Ch. 23.2 - Prob. 4LOCh. 23.3 - Prob. 1LOCh. 23.3 - Prob. 2LO
Ch. 23.3 - Prob. 3LOCh. 23.4 - Prob. 1LOCh. 23.4 - Prob. 2LOCh. 23.5 - Explain the adaptations of Homo erectus.Ch. 23.5 - Prob. 2LOCh. 23.5 - Prob. 3LOCh. 23.5 - Prob. 1BTSCh. 23.5 - Prob. 2BTSCh. 23.5 - Prob. 1BTBCh. 23.5 - Prob. 2BTBCh. 23.5 - Prob. 3BTBCh. 23 - Prob. 1ACh. 23 - Prob. 2ACh. 23 - Prob. 3ACh. 23 - 4. The fossil record offers direct evidence for...Ch. 23 - 5. A history of how species change over time...Ch. 23 - Prob. 6ACh. 23 - Prob. 7ACh. 23 - Prob. 8ACh. 23 - Prob. 9ACh. 23 - Prob. 10ACh. 23 - Prob. 11ACh. 23 - Prob. 12ACh. 23 - Prob. 13ACh. 23 - Prob. 14ACh. 23 - Prob. 15ACh. 23 - According to the fossil record. which of these...Ch. 23 - Bipedalism has many selective advantages,...Ch. 23 - In studying recent fossils of the genus Homo, such...Ch. 23 - Prob. 3TC
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