The mechanism for the base promoted chlorination of acetophenone is to be stated. Concept introduction: In base promoted halogenation, deprotonation of the α -carbon occurs to form the enolate ion. It attacks the electrophilic halogen to give monohalogenated ketone . The base promoted halogenation does not stop with the replacement of just single hydrogen. The product alpha haloketone is more reactive towards halogenation due to the presence of electron-withdrawing halogen which stabilizes the enolate ion.

Question

Want to see the full answer?

Answer 1

Question

Definition Definition Organic compounds that have a carbonyl group, C = O, as their functional group. The carbonyl group in ketones is placed somewhere in the middle of the molecular structure, which means, the C=O is attached to two alkyl groups or benzene rings. Just like all other homologous series, the naming of ketones is done using a common suffix “-one”. The general molecular formula is C n H 2n O. Functional group of a ketone

Chapter 22.5A, Problem 22.11P

Interpretation Introduction

Interpretation:

The mechanism for the base promoted chlorination of acetophenone is to be stated.

Concept introduction:

In base promoted halogenation, deprotonation of the α-carbon occurs to form the enolate ion. It attacks the electrophilic halogen to give monohalogenated ketone. The base promoted halogenation does not stop with the replacement of just single hydrogen. The product alpha haloketone is more reactive towards halogenation due to the presence of electron-withdrawing halogen which stabilizes the enolate ion.

Expert Solution & Answer

Want to see the full answer?

Check out a sample textbook solution

See solution

Students have asked these similar questions

O Predict the 'H NMR integration ratio for the following structure. IV I. 3 H A II. 1 H III. 2 H IV. 3 H I. 3 H B II. O H III. 2 H IV. 3 H I. 3 H C II. 2 H III. 2 H

205. From the definition of the Gibbs free energy, G = H - TS, derive the Gibbs-Helmholtz equation a (or (G)),- =- H T2

229. Show that ән (~~)--(*), др =V-T P

Answer 2

Question

Definition Definition Organic compounds that have a carbonyl group, C = O, as their functional group. The carbonyl group in ketones is placed somewhere in the middle of the molecular structure, which means, the C=O is attached to two alkyl groups or benzene rings. Just like all other homologous series, the naming of ketones is done using a common suffix “-one”. The general molecular formula is C n H 2n O. Functional group of a ketone

Chapter 22.5A, Problem 22.11P

Interpretation Introduction

Interpretation:

The mechanism for the base promoted chlorination of acetophenone is to be stated.

Concept introduction:

In base promoted halogenation, deprotonation of the α-carbon occurs to form the enolate ion. It attacks the electrophilic halogen to give monohalogenated ketone. The base promoted halogenation does not stop with the replacement of just single hydrogen. The product alpha haloketone is more reactive towards halogenation due to the presence of electron-withdrawing halogen which stabilizes the enolate ion.

Expert Solution & Answer

Want to see the full answer?

Check out a sample textbook solution

See solution

Answer 3

Question

Definition Definition Organic compounds that have a carbonyl group, C = O, as their functional group. The carbonyl group in ketones is placed somewhere in the middle of the molecular structure, which means, the C=O is attached to two alkyl groups or benzene rings. Just like all other homologous series, the naming of ketones is done using a common suffix “-one”. The general molecular formula is C n H 2n O. Functional group of a ketone

Chapter 22.5A, Problem 22.11P

Interpretation Introduction

Interpretation:

The mechanism for the base promoted chlorination of acetophenone is to be stated.

Concept introduction:

In base promoted halogenation, deprotonation of the α-carbon occurs to form the enolate ion. It attacks the electrophilic halogen to give monohalogenated ketone. The base promoted halogenation does not stop with the replacement of just single hydrogen. The product alpha haloketone is more reactive towards halogenation due to the presence of electron-withdrawing halogen which stabilizes the enolate ion.

Expert Solution & Answer

Want to see the full answer?

Check out a sample textbook solution

See solution

Answer 4

Question

Definition Definition Organic compounds that have a carbonyl group, C = O, as their functional group. The carbonyl group in ketones is placed somewhere in the middle of the molecular structure, which means, the C=O is attached to two alkyl groups or benzene rings. Just like all other homologous series, the naming of ketones is done using a common suffix “-one”. The general molecular formula is C n H 2n O. Functional group of a ketone

Chapter 22.5A, Problem 22.11P

Interpretation Introduction