Chapter 22, Problem 3EQ

Summary Introduction

To review:

The necessity to link chain A and B with β-galactosidase and the separation of the chains after the synthesis of the fusion protein in Escherichia coli.

Introduction:

Insulin is the first genetically engineered drug. Human insulin is responsible for regulating the uptake of glucose into fat and muscle cells. The beta pancreatic cells are responsible for producing insulin. The loss of these cells results in inadequate production of insulin.