EBK HUMAN PHYSIOLOGY
EBK HUMAN PHYSIOLOGY
7th Edition
ISBN: 9780133983401
Author: Silverthorn
Publisher: YUZU
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Chapter 22, Problem 19CC
Summary Introduction

To determine: The use of sitagliptin in the treatment of diabetes.

Introduction: Diabetes is categorized into two types: type 1 and type 2 diabetes. Type 2 diabetes is insulin dependent diabetes. People who have diabetes have reduced the production of insulin in their body leading to a delayed response to ingested glucose. In some cases, both resistance to insulin as well as reduced secretion of insulin is seen.

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The metabolic pathway below is used for the production of the purine nucleotides adenosine monophosphate (AMP) and guanosine monophosphate (GMP) in eukaryotic cells. Assume each arrow represents a reaction catalyzed by a different enzyme. Using the principles of feedback inhibition, propose a regulatory scheme for this pathway that ensures an adequate supply of both AMP and GMP, and prevents the buildup of Intermediates A through G when supplies of both AMP and GMP are adequate.
QUESTION 27 Label the structures marked A, B, C and explain the role of structure A. W plasma membrane For the toolbar, press ALT+F10 (PC) or ALT+FN+F10 (Mac). BIUS ☐ Paragraph Π " ΩΘΗ Β Open Sans, a... 10pt EE
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Chapter 22 Solutions

EBK HUMAN PHYSIOLOGY

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