Chapter 21.3, Problem 30AQP

a.

Summary Introduction

To determine:

The effect on X-inactivation of adding $\text{siRNA}$ that eliminated the products of Xist.

Introduction:

X-inactivation is the process in which one of the X-chromosome in females are inactivated permanently, which in turn suppress the transcription. All the females possess two X-chromosomes, which contain the ribonucleic acid (RNA) gene called Xist(X-inactive specific transcript).

b.

Summary Introduction

To determine:

The effect on X-inactivation of adding $\text{siRNA}$ that eliminated the products of Jpx.

Introduction:

X-inactivation is the process in which one of the X-chromosome in females are inactivated permanently, which in turn suppress the transcription. All the females possess two X-chromosomes, which contain the ribonucleic acid (RNA) gene called Xist(X-inactive specific transcript).