Campbell Biology in Focus
3rd Edition
ISBN: 9780134710679
Author: Lisa A. Urry, Michael L. Cain, Steven A. Wasserman, Peter V. Minorsky, Rebecca Orr
Publisher: PEARSON
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Chapter 20.2, Problem 1CC
Decide whether each of the following pairs of structures more likely represents analogy or homology, and explain your reasoning: (a) a porcupine's quills and a cactus's spines; (b) a cat’s paw and a human’s hand; (c) an owl’s wing and a hornet’s wing.
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Digoxin: Intravenous Bolus - Two Compartment Model
Drug
Digoxin
Route:
IV Bolus
Dose:
0.750 mg
Plasma Concentration Time Profile
Beta
Alpha
Time (hrs)
Conc (ng/ml)
LN
(ng/ml)
LN
(ng/ml)
LN
0.00
#NUM!
#NUM!
#NUM!
0.10
12.290
2.509
#NUM!
#NUMI
0.60
6.975
1.942
#NUM!
#NUMI
1.00
4.649
1.537
#NUM!
#NUMI
2.00
2.201
0.789
#NUM!
#NUM!
3.00
1.536
0.429
#NUM!
#NUM!
4.00
1.342
0.294
#NUM!
#NUM!
5.00
1.273
0.241
#NUM!
#NUMI
6.00
1.238
0.213
#NUM!
#NUM!
7.00
1.212
0.192
#NUM!
#NUM!
8.00
1.188
0.172
#NUMI
#NUM!
9.00
1.165
0.153
#NUM!
#NUMI
10.00
1.143
0.134
#NUMI
#NUM!
11.00
1.122
0.115
#NUM!
12.00
1.101
0.096
#NUMI
13.00
1.080
0.077
#NUMI
16.00
1.020
0.020
#NUMI
24.00
0.876
-0.132
#NUMI
Pharmacokinetic Parameters
Parameter
Value
Alpha
B
Beta
Units
ng/ml
hr-1
ng/ml
hr-1
CO
ng/ml
H.C
AUC
ng x hr/ml
Vc
Vbeta
Vss
C
L/hr
TK (alpha)
hr
TX (beta)
days
5+
F3
F4
F5
0+
F6
F7
%
6
95
14
#3
29
&
t
F8
F9
FW
EW
Linuron, a derivative of urea, is used as an herbicide. Linuron serum levels were measured in 4Kg
rabbits following a bolus IV injection of 10mg/kg.
Time (minutes)
Serum Linuron Levels (ug/ml)
following IV dose
10
15.48
20
8.60
30
5.90
45
3.78
60
2.42
90
1.49
120
0.93
180
0.60
240
0.41
300
0.29
360
0.22
Analyze this data and perform the necessary calculations to determine the following pharmacokinetic
parameters from the IV data: (5 points per parameter, 24 parameters/variables ■ 120 points
possible). You do NOT need to submit graphs or data tables.
Give the terminal regression line equation and R or R² value:
Give the x axis (name and units, if any) of the terminal line:
Give the y axis (name and units, if any) of the terminal line:
Give the residual regression line equation and R or R² value:
Give the x axis (name and units, if any) of the residual line:
Give the y axis (name and units, if any) of the residual line:
Chapter 20 Solutions
Campbell Biology in Focus
Ch. 20.1 - Based on the tree in Figure 20.4, are leopards...Ch. 20.1 - Which of the trees shown here depicts an...Ch. 20.1 - Prob. 3CCCh. 20.2 - Decide whether each of the following pairs of...Ch. 20.2 - WHAT IF? Suppose that two species, A and B, have...Ch. 20.3 - Prob. 1CCCh. 20.3 - The most parsimonious tree of evolutionary...Ch. 20.3 - Prob. 3CCCh. 20.4 - What is a molecular clock? What assumption...Ch. 20.4 - MAKE CONNECTIONS Review Concept 14.5. Then...
Ch. 20.4 - WHAT IF? Suppose a molecular clock dates the...Ch. 20.5 - Why is the kingdom Monera no longer considered a...Ch. 20.5 - Prob. 2CCCh. 20.5 - Prob. 3CCCh. 20 - In a comparison of birds and mammals, the...Ch. 20 - To apply parsimony to constructing a phylogenetic...Ch. 20 - Prob. 3TYUCh. 20 - Prob. 4TYUCh. 20 - Prob. 5TYUCh. 20 - If you were using cladistics to build a...Ch. 20 - Prob. 7TYUCh. 20 - SCIENTIFIC INQUIRY DRAW IT (a) Draw a phylogenetic...Ch. 20 - FOCUS ON EVOLUTION Darwin suggested looking at a...Ch. 20 - Prob. 10TYUCh. 20 - SYNTHESIZE YOUR KNOWLEDGE This West Indian manatee...
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