Human Biology, 14 Edition
Human Biology, 14 Edition
14th Edition
ISBN: 9781259245749
Author: Sylvia S. Mader Dr., Michael Windelspecht
Publisher: McGraw-Hill Education
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Chapter 20.1, Problem 1LO

Descrihe the characteristics of cancer cells that distinguish them from normal cells.

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22. Which of the following mutant proteins is expected to have a dominant negative effect when over-   expressed in normal cells?   a. mutant PI3-kinase that lacks the SH2 domain but retains the kinase function   b. mutant Grb2 protein that cannot bind to RTK   c. mutant RTK that lacks the extracellular domain   d. mutant PDK that has the PH domain but lost the kinase function   e. all of the above
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