Lifetime Physical Fitness and Wellness
15th Edition
ISBN: 9781337392686
Author: Wener W.K. Hoeger, Sharon A. Hoeger, Cherie I Hoeger, Amber L. Fawson
Publisher: Cengage Learning
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- ________ Although the incidence of neural tube defects in the United States declined post-folic acid fortification, some women are still at risk. Which of the following options represents a risk group for inadequate folate status and a neural tube defect affected pregnancy? a. Non-Hispanic Black women b. Non-Hispanic White women c. Asian Americans d. Hispanic Americansarrow_forwardAs outlined in this chapter, sex can be defined at several levels: chromosomal, gonadal, and phenotypic. To this we can add psychological sex, the sex one believes themselves to be. Determining someones sex is a complex issue that is often difficult to resolve, as the case of Bruce Reimer (see Section 7.1) illustrates. In spite of the complexity surrounding this issue, the International Olympic Committee (IOC) and the International Association of Athletics Federations (IAFF) still use sex testing on female athletes to determine whether they can compete in athletic events as females. This has led to serious personal, social, and legal issues, and the practice has been widely condemned and widely defended. Lets examine two such cases here. An Indian athlete, Santhi Soundarajan, finished second in the 800-meter run at the Asian Games in Doha, Qatar, in 2006. After the race, she was asked to take a sex test. According to press reports, the tests showed that she appeared to have abnormal chromosomes. An official stated that she had more Y chromosomes than allowed. As a result, she was stripped of her medal, banned from further competition by the Indian Olympic Association, and shunned by her local community. Before the race in Doha, Santhi had competed in 8 international competitions and won 12 medals. Sometime after this incident, she attempted suicide. She now runs a training school for athletes in Tamil Nadu, India. Although the number and types of tests done on Santhi have not been revealed, such tests usually involve examination of the external genitals, a chromosome analysis, and measurement of hormone levels. Suppose you were on the committee deciding whether Santhi could compete as a female. Consider each of the following hypothetical tests one at a time and base your conclusions only on the results of that test. The results of a physical examination show she has female genitals. On this basis, would you allow her to keep her medal and compete as a female in future races? Suppose the results of a chromosomal analysis shows that she has an XY chromosome set and is chromosomally male. Would you allow her to keep her medal and compete as a female? Lastly, suppose a test for hormone levels shows that she has levels of the male sex hormone testosterone that are higher than average for females but at least 10 times lower than the average for males. Would you allow her to keep her medal and compete in future races as a female? Now, put the results of all three tests together, and consider them as a whole. What are your conclusions? Now, lets consider the case of a South African runner, Caster Semenya, who won the 800-meter run at the World Championships held in Berlin, Germany, in 2009. After the race, she was asked to undergo sex testing. The IAAF stated that the tests were requested to ascertain whether she had a rare medical condition that gave her an unfair physical advantage. The nature of the tests and their results were not released, but press reports indicate that she did not have ovaries or a uterus, and had testosterone levels intermediate between the averages for males and females. In the end, the IAAF agreed to keep the results of her tests confidential, and Caster was allowed to keep her medal and return to international competition in 2010. In both cases, what the IAAF considers the threshold for determining who can compete as a female has not been stated. Would you recommend that testing of female athletes be continued to ensure that males do not compete as females? Or should all such testing be banned?arrow_forwardThe following family has a history of inherited breast cancer. Betty (grandmother) does not carry the gene. Don, her husband, does. Dons mother and sister had breast cancer. One of Betty and Dons daughters (Sarah) has breast cancer; the other (Karen) does not. Sarahs daughters are in their 30s. Dawn, 33, has breast cancer; Debbie, 31, does not. Debbie is wondering if she will get the disease because she looks like her mother. Dawn is wondering if her 2-year-old daughter (Nicole) will get the disease. a. Draw a pedigree indicating affected individuals and identify all individuals. b. What is the most likely mode of inheritance of this trait? c. What are Dons genotype and phenotype? d. What is the genotype of the unaffected women (Betty and Karen)? e. A genetic marker has been found that maps very close to the gene. Given the following marker data for chromosomes 4 and 17, which chromosome does this gene map to? f. Using the same genetic marker, Debbie and Nicole were tested. The results are shown in the following figure. Based on their genotypes, is either of them at increased risk for breast cancer?arrow_forward
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