Human Biology: Concepts and Current Issues (8th Edition)
8th Edition
ISBN: 9780134042435
Author: Michael D. Johnson
Publisher: PEARSON
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Chapter 2, Problem 3CR
Explain why polar and charged molecules tend to be soluble in water.
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The following table is from Kumar et. al. Highly Selective Dopamine D3 Receptor (DR) Antagonists and Partial Agonists Based on Eticlopride and the D3R Crystal Structure: New Leads for Opioid Dependence Treatment. J. Med Chem 2016.
The following figure is from Caterina et al. The capsaicin receptor: a heat activated ion channel in the
pain pathway. Nature, 1997. Black boxes indicate capsaicin, white circles indicate resinferatoxin.
You are a chef in a fancy new science-themed restaurant. You have a recipe that calls for 1 teaspoon of resinferatoxin, but you feel uncomfortable serving foods with "toxins" in them. How much capsaicin could you substitute instead?
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Chapter 2 Solutions
Human Biology: Concepts and Current Issues (8th Edition)
Ch. 2 -
1. Who do you think should be responsible for...Ch. 2 - Prob. 2QCCh. 2 - Describe the electrical charges and relative...Ch. 2 -
2. Explain why two atoms of hydrogen tend to...Ch. 2 -
3. Explain why polar and charged molecules tend...Ch. 2 - How is a covalent bond different from an ionic...Ch. 2 - Compare and contrast potential energy and kinetic...Ch. 2 - Distinguish between saturated and unsaturated...Ch. 2 - Describe the process known as dehydration...Ch. 2 - Explain why proteins come in an almost unlimited...
Ch. 2 -
9. Discuss the importance of enzymes in living...Ch. 2 -
10. Describe the role of ATP in energy transfer...Ch. 2 - If a molecule of starch is repeatedly hydrolyzed,...Ch. 2 - Which of these molecules would be described as...Ch. 2 -
3. _______bonds form between the oxygen and...Ch. 2 - 13C and 14C are ______ of carbon. a. isotopes b....Ch. 2 - Which of the following substances has the lowest...Ch. 2 - When sugar is dissolved in water, sugar is the...Ch. 2 - A monosaccharide is to a polysaccharide as an...Ch. 2 -
8. Which of these bonds is the easiest to...Ch. 2 -
9. The primary structure of a protein is...Ch. 2 -
10. DNA ultimately contains the instructions for...Ch. 2 - If one strand of DNA has the sequence...Ch. 2 - Which of the following is true regarding the...Ch. 2 -
13. Which of the following is true regarding...Ch. 2 - Synthesis of proteins requires the input of...Ch. 2 - Prob. 15TYCh. 2 - Prob. 1AWKCh. 2 - Prob. 2AWKCh. 2 - Many people use cholesterol-lowering drugs to...Ch. 2 - Prob. 4AWKCh. 2 -
5. Coca-Cola is a very acidic drink; its pH is...
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- 1. Match each vocabulary term to its best descriptor A. affinity B. efficacy C. inert D. mimic E. how drugs move through body F. how drugs bind Kd Bmax Agonist Antagonist Pharmacokinetics Pharmacodynamicsarrow_forward50 mg dose of a drug is given orally to a patient. The bioavailability of the drug is 0.2. What is the volume of distribution of the drug if the plasma concentration is 1 mg/L? Be sure to provide units.arrow_forwardDetermine Kd and Bmax from the following Scatchard plot. Make sure to include units.arrow_forward
- Choose a catecholamine neurotransmitter and describe/draw the components of the synapse important for its signaling including synthesis, packaging into vesicles, receptors, transporters/degradative enzymes. Describe 2 drugs that can act on this system.arrow_forwardThe following figure is from Caterina et al. The capsaicin receptor: a heat activated ion channel in the pain pathway. Nature, 1997. Black boxes indicate capsaicin, white circles indicate resinferatoxin. a) Which has a higher potency? b) Which is has a higher efficacy? c) What is the approximate Kd of capsaicin in uM? (you can round to the nearest power of 10)arrow_forwardWhat is the rate-limiting-step for serotonin synthesis?arrow_forward
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