Fundamentals of Biostatistics
8th Edition
ISBN: 9781305268920
Author: Bernard Rosner
Publisher: Cengage Learning
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Chapter 2, Problem 34P
Activated-protein-C (APC) resistance is a serum marker that has been associated with thrombosis (the formation of blood clots often leading to heart attacks) among adults. A study assessed this risk factor among adolescents. To assess the reproducibility of the assay, a split-sample technique was used in which a blood sample was provided by 10 people; each sample was split into two aliquots (sub-samples), and each aliquot was assessed separately. Table 2.19 gives the results.
Table 2.19 APC resistance split-samples data
Compute the average CV over the 10 subjects as an overall measure of variability of the assay. In general, a CV of <10% is considered excellent, ≥10% and <20% is considered good, ≥20% and <30% is considered fair, and ≥30% is considered poor.
How would you characterize the reliability of the APC assay based on these criteria?
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Chapter 2 Solutions
Fundamentals of Biostatistics
Ch. 2.6 - When is it appropriate to use the arithmetic mean...Ch. 2.6 - How does the geometric mean differ from the...Ch. 2.6 - What is the difference between the standard...Ch. 2.8 - What is a stem-and-leaf plot? How does it differ...Ch. 2.8 - Prob. B.2RECh. 2.8 - Consider the stem-and-leaf plot in Figure 2.6. Is...Ch. 2.8 - What is a box plot? What additional information...Ch. 2 - The data in Table 2.13 are a sample from a larger...Ch. 2 - The data in Table 2.13 are a sample from a larger...Ch. 2 - It is of clinical interest to know if the duration...
Ch. 2 - Suppose the scale for a data set is changed by...Ch. 2 - Suppose the scale for a data set is changed by...Ch. 2 - Suppose the scale for a data set is changed by...Ch. 2 - Suppose the scale for a data set is changed by...Ch. 2 - A man runs 1 mile approximately once per weekend....Ch. 2 - A man runs 1 mile approximately once per weekend....Ch. 2 - A man runs 1 mile approximately once per weekend....Ch. 2 - A man runs 1 mile approximately once per weekend....Ch. 2 - A man runs 1 mile approximately once per weekend....Ch. 2 - The data in Table 2.15 are a sample of cholesterol...Ch. 2 - The data in Table 2.15 are a sample of cholesterol...Ch. 2 - The data in Table 2.15 are a sample of cholesterol...Ch. 2 - The data in Table 2.15 are a sample of cholesterol...Ch. 2 - The data in Table 2.15 are a sample of cholesterol...Ch. 2 - In an experiment that examined the effect of body...Ch. 2 - In an experiment that examined the effect of body...Ch. 2 - Table 2.17 Format for FEV.DAT The data in Table...Ch. 2 - Forced expiratory volume (FEV) is an index of...Ch. 2 - Forced expiratory volume (FEV) is an index of...Ch. 2 - Prob. 26PCh. 2 - The food-frequency questionnaire (FFQ) is an...Ch. 2 - In Section 2.9, we described Data Set LEAD.DAT (at...Ch. 2 - In Section 2.9, we described Data Set LEAD.DAT (at...Ch. 2 - Activated-protein-C (APC) resistance is a serum...Ch. 2 - Activated-protein-C (APC) resistance is a serum...Ch. 2 - A study was conducted to demonstrate that soy...Ch. 2 - A study was conducted to demonstrate that soy...Ch. 2 - A study was conducted to demonstrate that soy...Ch. 2 - Prob. 38PCh. 2 - In Section 2.10, we described Data Set BONEDEN.DAT...Ch. 2 - What impression do you have of the relationship...Ch. 2 - In Section 2.10, we described Data Set BONEDEN.DAT...Ch. 2 - In Section 2.10, we described Data Set BONEDEN.DAT...Ch. 2 - Prob. 43PCh. 2 - Prob. 44PCh. 2 - Prob. 45PCh. 2 - Answer Problems 2.382.40 for BMD for the femoral...Ch. 2 - The Left Ventricular Mass lndex (LVMI) is a...Ch. 2 - Prob. 48PCh. 2 - Prob. 49PCh. 2 - The Left Ventricular Mass lndex (LVMI) is a...
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