ORGANIC CHEM PRINT STUDY GDE & SSM
ORGANIC CHEM PRINT STUDY GDE & SSM
4th Edition
ISBN: 9781119810650
Author: Klein
Publisher: WILEY
Question
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Chapter 19.6, Problem 14PTS

(a)

Interpretation Introduction

Interpretation:

The plausible mechanism should be drawn for the following transformation.

Concept Introduction:

Imine formation:

Imine formation is formed when any primary amine reacts with an aldehydes or ketone under appropriate condition.

It requires an acid catalyst for fast reaction; otherwise this reaction is very slow.

The acid is needed for elimination of water molecule.

Proceeds Imine formation through six steps:-

1) Nucleophilic attack

2) Proton transfer

3) Proton transfer

4) Proton transfer

5) Loss of leaving group

6) Proton transfer

The protonated amines are usually called as ammonium ion.

Imine is popularly known as Schiff base.

To Draw: The following transformation of the plausible mechanism

(b)

Interpretation Introduction

Interpretation:

The plausible mechanism should be drawn for the following transformation.

Concept Introduction:

Imine formation:

Imine formation is formed when any primary amine reacts with an aldehydes or ketone under appropriate condition.

It requires an acid catalyst for fast reaction; otherwise this reaction is very slow.

The acid is needed for elimination of water molecule.

Proceeds Imine formation through six steps:-

1) Nucleophilic attack

2) Proton transfer

3) Proton transfer

4) Proton transfer

5) Loss of leaving group

6) Proton transfer

The protonated amines are usually called as ammonium ion.

Imine is popularly known as Schiff base.

To Draw: The following transformation of the plausible mechanism

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