The effect of the absence of the following proteins in the nucleotide excision repair (NER) mechanism and the condition of the DNA (deoxyribonucleic acid) if the repair mechanism was to occur without them: UvrA UvrC UvrD DNA polymerase Introduction: NER is one of the major DNA repair mechanisms in a cell. This mechanism works by removing the stretch of DNA which has the error and then replacing it with freshly synthesized DNA. A number of proteins are involved in the mechanism, such as UvrA, UvrB, UvrC and others. This system corrects many kinds of errors, such as chemically modified bases, thymine dimers and crosslinks in DNA.

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Chapter 19, Problem 31CONQ

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The effect of the absence of the following proteins in the nucleotide excision repair (NER) mechanism and the condition of the DNA (deoxyribonucleic acid) if the repair mechanism was to occur without them:

UvrA

UvrC

UvrD

DNA polymerase

Introduction:

NER is one of the major DNA repair mechanisms in a cell. This mechanism works by removing the stretch of DNA which has the error and then replacing it with freshly synthesized DNA. A number of proteins are involved in the mechanism, such as UvrA, UvrB, UvrC and others. This system corrects many kinds of errors, such as chemically modified bases, thymine dimers and crosslinks in DNA.

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