
Concept explainers
Interpretation:
The complete structural formula for the peptide trp-pro-gly-tyr has to be drawn, and the bond that is broken under action of chymotrypsin has to be determined.
Concept Introduction:
Proteolytic enzymes that cleave the peptide bond are found in the pancreases and are often referred to as serine proteases because of the presence of a nucleophilic serine at the active site of the active site. They are classified on the basis of the substrate specificity. For example, the trypsin cleaves specifically at the carboxyl end of positively charged amino acids such as arginine or lysine except for the cases when they are followed by amino acid proline.
Chymotrypsin cleaves at the carboxyl-terminal of

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Chapter 19 Solutions
General, Organic, and Biochemistry
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