Chapter 19, Problem 19.38P

Interpretation Introduction

(a)

Interpretation:

The synthesis of given Grignard reagent from an alkyl, alkenyl, alkynyl, or aryl halide is to be suggested.

Concept introduction:

Grignard reagent can be prepared from an alkyl, alkenyl, alkynyl, or aryl halide where the $\text{C}-\text{X}$ bond is converted to $\text{C}-\text{MgX}$. The halides, on reaction with $\text{Mg}$ metal in an ether, forms Grignard reagent.

Answer to Problem 19.38P

The synthesis of the given Grignard reagent from an alkynyl halide is:

Explanation of Solution

The given Grignard reagent is:

The given Grignard reagent can be prepared from alkynyl bromide as $\text{MgBr}$ is bonded to triple bonded carbon. The carbon bonded to $\text{Mg}$ is bonded to $\text{Br}$ in alkynyl bromide. Thus, alkynyl bromide on reaction with $\text{Mg}$ metal in ether yields this Grignard reagent.

Conclusion

The synthesis of the given Grignard reagent is provided by identifying alkynyl halide.

Interpretation Introduction

(b)

Interpretation:

The synthesis of given Grignard reagent from an alkyl, alkenyl, alkynyl, or aryl halide is to be suggested.

Concept introduction:

Grignard reagent can be prepared from an alkyl, alkenyl, alkynyl, or aryl halide where the $\text{C}-\text{X}$ bond is converted to $\text{C}-\text{MgX}$. The halides, on reaction with $\text{Mg}$ metal in an ether forms Grignard reagent.

Answer to Problem 19.38P

The synthesis of given Grignard reagent from an alkyl halide is:

Explanation of Solution

The given Grignard reagent is:

The given Grignard reagent can be prepared from alkyl iodide as $\text{MgI}$ is bonded to ${\text{sp}}^{\text{3}}$ carbon. The carbon bonded to $\text{Mg}$ is bonded to $\text{I}$ in the alkyl iodide. Thus, alkyl iodide on reaction with $\text{Mg}$ metal in ether yields this Grignard reagent.

Conclusion

The synthesis of given Grignard reagent is provided by identifying alkyl halide.

Interpretation Introduction

(c)

Interpretation:

The synthesis of given Grignard reagent from an alkyl, alkenyl, alkynyl, or aryl halide is to be suggested.

Concept introduction:

Grignard reagent can be prepared from an alkyl, alkenyl, alkynyl, or aryl halide where the $\text{C}-\text{X}$ bond is converted to $\text{C}-\text{MgX}$. The halides, on reaction with $\text{Mg}$ metal in an ether forms Grignard reagent.

Answer to Problem 19.38P

The synthesis of given Grignard reagent from an aryl halide is:

Explanation of Solution

The given Grignard reagent is:

The given Grignard reagent can be prepared from aryl bromide as $\text{MgBr}$ is bonded to carbon of aromatic ring. The carbon bonded to $\text{Mg}$ is bonded to $\text{Br}$ in aryl bromide. Thus, aryl bromide on reaction with $\text{Mg}$ metal in ether yields this Grignard reagent.

Conclusion

The synthesis of the given Grignard reagent is provided by identifying aryl halide.

Interpretation Introduction

(d)

Interpretation:

The synthesis of given Grignard reagent from an alkyl, alkenyl, alkynyl, or aryl halide is to be suggested.

Concept introduction:

Grignard reagent can be prepared from an alkyl, alkenyl, alkynyl, or aryl halide where the $\text{C}-\text{X}$ bond is converted to $\text{C}-\text{MgX}$. The halides on reaction with $\text{Mg}$ metal in an ether forms Grignard reagent.

Answer to Problem 19.38P

The synthesis of the given Grignard reagent from an aryl halide is:

Explanation of Solution

The given Grignard reagent is:

The given Grignard reagent can be prepared from aryl bromide as $\text{MgBr}$ is bonded to carbon of aromatic ring. The carbon bonded to $\text{Mg}$ is bonded to $\text{Br}$ in aryl bromide. Thus, aryl bromide on reaction with $\text{Mg}$ metal in ether yields this Grignard reagent.

Conclusion

The synthesis of given Grignard reagent is provided by identifying the aryl halide.

Interpretation Introduction

(e)

Interpretation:

The synthesis of given Grignard reagent from an alkyl, alkenyl, alkynyl, or aryl halide is to be suggested.

Concept introduction:

Grignard reagent can be prepared from an alkyl, alkenyl, alkynyl, or aryl halide where the $\text{C}-\text{X}$ bond is converted to $\text{C}-\text{MgX}$. The halides on reaction with $\text{Mg}$ metal in an ether forms Grignard reagent.

Answer to Problem 19.38P

The synthesis of given Grignard reagent from an alkyl halide is:

Explanation of Solution

The given Grignard reagent is:

The given Grignard reagent can be prepared from alkyl iodide as $\text{MgI}$ is bonded to ${\text{sp}}^{\text{3}}$ carbon. The carbon bonded to $\text{Mg}$ is bonded to $\text{I}$ in alkyl iodide. Thus, alkyl iodide on reaction with $\text{Mg}$ metal in ether yields this Grignard reagent.

Conclusion

The synthesis of given Grignard reagent is provided by identifying alkyl halide.

Interpretation Introduction

(f)

Interpretation:

The synthesis of given Grignard reagent from an alkyl, alkenyl, alkynyl, or aryl halide is to be suggested.

Concept introduction:

Grignard reagent can be prepared from an alkyl, alkenyl, alkynyl, or aryl halide where the $\text{C}-\text{X}$ bond is converted to $\text{C}-\text{MgX}$. The halides on reaction with $\text{Mg}$ metal in an ether forms Grignard reagent.

Answer to Problem 19.38P

The synthesis of the given Grignard reagent from an aryl halide is:

Explanation of Solution

The given Grignard reagent is:

The given Grignard reagent can be prepared from aryl chloride as $\text{MgCl}$ is bonded to carbon of aromatic ring. The carbon bonded to $\text{Mg}$ is bonded to $\text{Cl}$ in aryl chloride. Thus, aryl chloride on reaction with $\text{Mg}$ metal in ether yields this Grignard reagent.

Conclusion

The synthesis of given Grignard reagent is provided by identifying aryl halide.