The concentration at which dideoxyribonucleotide produces a greater number of long complementary sequences. Introduction: DNA (deoxyribonucleic acid) sequencing is the method used to determine the sequences of the four nucleotide sequences of the DNA strand. The DNA sequences were obtained in the early 1970s. Frederick Sanger used the chain termination method to determine the sequences of nucleic acid bases in a DNA fragment.

Question

According to a recent study, 1 out of 50,000 people will be diagnosed with cystic fibrosis. Cystic fibrosis can be caused by a mutant form of the CFTR gene (dominant gene symbol is F and mutant is f). A. Using the rate of incidence above, what is the frequency of carriers of the cystic fibrosis allele for CFTR in the US? (3 pts) B. In a clinical study, 400 people from the population mentioned in (A.) were genotyped for BRCA1 Listed below are the results. Are these results in Hardy- Weinberg equilibrium? Use Chi Square to show whether or not they are. (3 pts) BRCA1 genotype # of women 390 BB Bb bb 10 0 12pt Paragraph L BIUAV V T² v V

Answer 1

Question

Chapter 19, Problem 12TYK

Summary Introduction

To review:

The concentration at which dideoxyribonucleotide produces a greater number of long complementary sequences.

Introduction:

DNA (deoxyribonucleic acid) sequencing is the method used to determine the sequences of the four nucleotide sequences of the DNA strand. The DNA sequences were obtained in the early 1970s. Frederick Sanger used the chain termination method to determine the sequences of nucleic acid bases in a DNA fragment.

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According to a recent study, 1 out of 50,000 people will be diagnosed with cystic fibrosis. Cystic fibrosis can be caused by a mutant form of the CFTR gene (dominant gene symbol is F and mutant is f). A. Using the rate of incidence above, what is the frequency of carriers of the cystic fibrosis allele for CFTR in the US? (3 pts) B. In a clinical study, 400 people from the population mentioned in (A.) were genotyped for BRCA1 Listed below are the results. Are these results in Hardy- Weinberg equilibrium? Use Chi Square to show whether or not they are. (3 pts) BRCA1 genotype # of women 390 BB Bb bb 10 0 12pt Paragraph L BIUAV V T² v V

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