Interpretation:
A suitable solvent to analyze the mixture of alcohol and
Concept introduction:
Thin-layer chromatography is an analytical technique used to identify whether two compounds are identical or not and also to find the number of compounds in a mixture.
Metal, glass or plates made of plastics are utilized in TLC that are coated by a thin layer of adsorbent and it acts as a stationary phase. The stationary phase usually used is polar silica gel. A mixture of solvents or single pure solvent is the mobile. It is also known as a developing agent. Mostly nonvolatile solid organic samples are analyzed by thin-layer chromatography.However, TLC cannot be used for volatile liquid compounds because it leads to loss of the sample by evaporation from the TLC plate.
In TLC analysis, mixture in a low quantity is taken for separation and dissolved in the suitable solvent and applied on the TLC plate. Then TLC plate is kept in the closed chamber immersed in mobile phase known as developing solvent. Through capillary action the solvent rises on the stationary phase. As the solvent rises on the plate, the sample is distributed between the mobile phase and the stationary phase on the basis of their retention values. The more the compound interacts with the stationary phase, the more slowly it moves on the TLC plate. When silica gel that is polar in nature behaves as the stationary phase then mobile solvent rises with the nonpolar substances up on the plate most rapidly. In the chromatogram the polar substances rise up plate with lowest rate.
The ratio of distances covered by the compound to the distance covered by developing solvent or mobile front is known as retention factor
The
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Chapter 18 Solutions
LABORATORY TECHNIQUES IN ORGANIC CHEMIS
- If a reaction occurs, what would be the major products? Please include a detailed explanation as well as a drawing showing how the reaction occurs and what the final product is.arrow_forwardWould the following organic synthesis occur in one step? Add any missing products, required catalysts, inorganic reagents, and other important conditions. Please include a detailed explanation and drawings showing how the reaction may occur in one step.arrow_forward(a) Sketch the 'H NMR of the following chemical including the approximate chemical shifts, the multiplicity (splitting) of all signals and the integration (b) How many signals would you expect in the 13C NMR? CH3arrow_forward
- Draw the Show the major and minor product(s) for the following reaction mechanisms for both reactions and show all resonance structures for any Explain why the major product is favoured? intermediates H-Brarrow_forwardChoose the right answerarrow_forward8. What is the major product of the following reaction? KMnO4 b a TOH OH OH C d OH "OH HO OH OHarrow_forward
- Choose the right answerarrow_forward3. Draw ALL THE POSSBILE PRODUCTS AND THE MECHANISMS WITH ALL RESONANCE STRUCTURES. Explain using the resonance structures why the major product(s) are formed over the minor product(s). H₂SO4, HONO CHarrow_forward7. Provide the product(s), starting material(s) and/or condition(s) required for the No mechanisms required. below reaction HO + H-I CI FO Br2, FeBr3 O I-Oarrow_forward
- 6. Design the most efficient synthesis of the following product starting from phenot Provide the reaction conditions for each step (more than one step is required) and explain the selectivity of each reaction. NO MECHANISMS ARE REQUIRED. OH step(s) CIarrow_forwardWhat is the skeletal structure of the product of the following organic reaction?arrow_forwardIf a reaction occurs, what would be the major products? Please include a detailed explanation as well as a drawing showing how the reaction occurs and what the final product is.arrow_forward
EBK A SMALL SCALE APPROACH TO ORGANIC LChemistryISBN:9781305446021Author:LampmanPublisher:CENGAGE LEARNING - CONSIGNMENT