ORGANIC CHEMISTRYPKGDRL+MLCRL MDL
3rd Edition
ISBN: 9781119416746
Author: Klein
Publisher: WILEY
expand_more
expand_more
format_list_bulleted
Question
Chapter 17.5, Problem 16CC
Interpretation Introduction
Interpretation For the given Meclizine, its sedative property should explained
Concept introduction:
- Anti-histamines are drugs which treat allergic. It gives relief from nausea and vomiting
- Pharmacophore is a part of molecular structure that has two
aromatic rings separated by one carbon atom, and a tertiaryamine - Meclizine is antihistamine which prevents nausea and vomiting
Expert Solution & Answer
Want to see the full answer?
Check out a sample textbook solution
Students have asked these similar questions
PQ-10. What is the major product of this reaction?
(A)
(C)
930
Me
HO
O=S=O
O-8-CF,
C
어
Me
H+
OH
270
O
0-5-0
O=S=O
O-S-CF
CF3
2
Predict the major organic product(s) of the following reactions. Include stereochemistry when necessary. Write NR if no reaction, try to explain.
Q2: Explain why epoxides that react in an SN1 manner will not show any stereochemical
inversion in the product.
Q3: Rationalize why Alcohol B will react under the indicated reaction conditions, but Alcohol A
will not.
A
☑
OH
B
OH
PBr3
R-Br
Chapter 17 Solutions
ORGANIC CHEMISTRYPKGDRL+MLCRL MDL
Ch. 17.2 - Prob. 1LTSCh. 17.2 - Prob. 1PTSCh. 17.2 - Prob. 2PTSCh. 17.2 - Prob. 3PTSCh. 17.2 - Prob. 4PTSCh. 17.2 - Prob. 5ATSCh. 17.4 - Prob. 6CCCh. 17.4 - Prob. 7CCCh. 17.4 - Prob. 8CCCh. 17.4 - Prob. 9CC
Ch. 17.5 - Prob. 10CCCh. 17.5 - Prob. 2LTSCh. 17.5 - Prob. 11PTSCh. 17.5 - Prob. 12ATSCh. 17.5 - Prob. 3LTSCh. 17.5 - Prob. 13PTSCh. 17.5 - Prob. 14ATSCh. 17.5 - Prob. 15ATSCh. 17.5 - Prob. 16CCCh. 17.6 - Prob. 17CCCh. 17.6 - Prob. 4LTSCh. 17.6 - Prob. 18PTSCh. 17.7 - Prob. 5LTSCh. 17.7 - Prob. 20PTSCh. 17.7 - Prob. 21ATSCh. 17.8 - Prob. 22CCCh. 17.8 - Prob. 23CCCh. 17 - Prob. 24PPCh. 17 - Prob. 25PPCh. 17 - Prob. 26PPCh. 17 - Prob. 27PPCh. 17 - Prob. 28PPCh. 17 - Prob. 29PPCh. 17 - Prob. 30PPCh. 17 - Prob. 31PPCh. 17 - Prob. 32PPCh. 17 - Prob. 33PPCh. 17 - Prob. 34PPCh. 17 - Prob. 35PPCh. 17 - Prob. 36PPCh. 17 - Prob. 37PPCh. 17 - Prob. 38PPCh. 17 - Prob. 39PPCh. 17 - Prob. 40PPCh. 17 - Prob. 41PPCh. 17 - Prob. 42PPCh. 17 - Prob. 43PPCh. 17 - Prob. 44PPCh. 17 - Prob. 45PPCh. 17 - Prob. 46PPCh. 17 - Prob. 47PPCh. 17 - Prob. 48IPCh. 17 - Prob. 49IPCh. 17 - Prob. 50IPCh. 17 - Prob. 51IPCh. 17 - Prob. 52IPCh. 17 - Prob. 53IPCh. 17 - Prob. 54IPCh. 17 - Prob. 55IPCh. 17 - Prob. 56IPCh. 17 - Prob. 57IPCh. 17 - Prob. 58IPCh. 17 - Prob. 59IPCh. 17 - Prob. 60IPCh. 17 - Prob. 61IPCh. 17 - Prob. 62IPCh. 17 - Prob. 63IPCh. 17 - Prob. 64IPCh. 17 - Prob. 65IPCh. 17 - Prob. 66IPCh. 17 - Prob. 67IPCh. 17 - Prob. 68IPCh. 17 - Prob. 69IPCh. 17 - Prob. 70CPCh. 17 - Prob. 71CPCh. 17 - Prob. 72CPCh. 17 - Prob. 73CPCh. 17 - Prob. 74CP
Knowledge Booster
Similar questions
- Q1: Predict the major organic product(s) of the following reactions. Include stereochemistry when necessary. Write NR if no reaction, try to explain. 1.) LDA, THF 2.) СОН CI OH H2SO4, heat OH m...... OH 1.) PCC, CH2Cl2 2.) CH3CH2MgBr, THF 3.) H3O+ 4.) TsCl, pyr 5.) tBuOK, tBuOH 1.) SOCI 2, CHCI 3 2.) CH3CH2ONA, DMF OH 1.) HBr 2.) Mg, THF 3.) H₂CO, THE 4.) H3O+ OH NaH, THFarrow_forwardWhat is the stepwise mechanism for this reaction?arrow_forwardDraw the major product of this reactionarrow_forward
- Please provide the IUPAC name for the compound shown herearrow_forwardProblem 6-29 Identify the functional groups in the following molecules, and show the polarity of each: (a) CH3CH2C=N CH, CH, COCH (c) CH3CCH2COCH3 NH2 (e) OCH3 (b) (d) O Problem 6-30 Identify the following reactions as additions, eliminations, substitutions, or rearrangements: (a) CH3CH2Br + NaCN CH3CH2CN ( + NaBr) Acid -OH (+ H2O) catalyst (b) + (c) Heat NO2 Light + 02N-NO2 (+ HNO2) (d)arrow_forwardPredict the organic product of Y that is formed in the reaction below, and draw the skeletal ("line") structures of the missing organic product. Please include all steps & drawings & explanations.arrow_forward
- Please choose the best reagents to complete the following reactionarrow_forwardProblem 6-17 Look at the following energy diagram: Energy Reaction progress (a) Is AG for the reaction positive or negative? Label it on the diagram. (b) How many steps are involved in the reaction? (c) How many transition states are there? Label them on the diagram. Problem 6-19 What is the difference between a transition state and an intermediate? Problem 6-21 Draw an energy diagram for a two-step reaction with Keq > 1. Label the overall AG°, transition states, and intermediate. Is AG° positive or negative? Problem 6-23 Draw an energy diagram for a reaction with Keq = 1. What is the value of AG° in this reaction?arrow_forwardProblem 6-37 Draw the different monochlorinated constitutional isomers you would obtain by the radical chlorination of the following compounds. (b) (c) Problem 6-39 Show the structure of the carbocation that would result when each of the following alkenes reacts with an acid, H+. (a) (b) (c)arrow_forward
arrow_back_ios
SEE MORE QUESTIONS
arrow_forward_ios
Recommended textbooks for you
ChemistryChemistryISBN:9781305957404Author:Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCostePublisher:Cengage Learning
ChemistryChemistryISBN:9781259911156Author:Raymond Chang Dr., Jason Overby ProfessorPublisher:McGraw-Hill Education
Principles of Instrumental AnalysisChemistryISBN:9781305577213Author:Douglas A. Skoog, F. James Holler, Stanley R. CrouchPublisher:Cengage Learning
Organic ChemistryChemistryISBN:9780078021558Author:Janice Gorzynski Smith Dr.Publisher:McGraw-Hill Education
Chemistry: Principles and ReactionsChemistryISBN:9781305079373Author:William L. Masterton, Cecile N. HurleyPublisher:Cengage Learning
Elementary Principles of Chemical Processes, Bind...ChemistryISBN:9781118431221Author:Richard M. Felder, Ronald W. Rousseau, Lisa G. BullardPublisher:WILEY
Chemistry
Chemistry
ISBN:9781305957404
Author:Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste
Publisher:Cengage Learning
Chemistry
Chemistry
ISBN:9781259911156
Author:Raymond Chang Dr., Jason Overby Professor
Publisher:McGraw-Hill Education
Principles of Instrumental Analysis
Chemistry
ISBN:9781305577213
Author:Douglas A. Skoog, F. James Holler, Stanley R. Crouch
Publisher:Cengage Learning
Organic Chemistry
Chemistry
ISBN:9780078021558
Author:Janice Gorzynski Smith Dr.
Publisher:McGraw-Hill Education
Chemistry: Principles and Reactions
Chemistry
ISBN:9781305079373
Author:William L. Masterton, Cecile N. Hurley
Publisher:Cengage Learning
Elementary Principles of Chemical Processes, Bind...
Chemistry
ISBN:9781118431221
Author:Richard M. Felder, Ronald W. Rousseau, Lisa G. Bullard
Publisher:WILEY