Chapter 16, Problem 3CS

Summary Introduction

To determine:

The reason sickle cell anemic patients suffer from more kidney complications.

Introduction:

The mutation of normal genes leads to the production of abnormal proteins; thus, it changes the anatomy as well the physiology of certain system and its components. Sickle cell trait (SCT) can be defined as a genetic disorder of single gene mutation in which a single base pair substitution occurs in the gene encoding the chain of hemoglobin (ß − globin).