
To explain: The homeostasis of hormones.
Concept introduction: Hormones are the chemical messengers that are secreted by the endocrine system. The hormone receptors may be found in the plasma membrane or in the intracellular compartment of the target cell. Homeostasis is the regulation of the internal conditions of the body to maintain an optimum internal environment despite changing external conditions.

Explanation of Solution
Endocrine cells or neurosecretory cells secrete hormones into the extracellular fluids that are signaling molecules. The secreted hormones reach the target cells through the bloodstream. Hormones bind only to specific cells based on the corresponding receptors, and they act through chemical signals. They are responsible for key homeostatic process by regulating the blood-glucose levels, and blood pressure in the body. The β-cells and α-cells of the pancreas secrete insulin and glucagon respectively to control the blood-glucose concentration. Insulin controls the uptake of glucose by transporting glucose into cells and lowers the blood glucose level. Glucagon controls the release of glucose by glycogenolysis and increases blood glucose level. Blood pressure is controlled by the antidiuretic hormone that is secreted by the pituitary gland. This hormone conserves the water volume in the body by dropping the amount of water passed out as urine.
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Chapter 16 Solutions
Pathophysiology for the Health Professions
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