The fact that “inversions and reciprocal translocations are less lethal than aneuploidy, duplication, deletions and nonreciprocal translocation”. Concept introduction : The aberration in chromosome structure and function can be caused due to aneuploidy, duplication, deletions and translocations. These can alter the chromosome to cause genetic disorders. Aneuploidy is a type of chromosomal alteration in which the number of chromosome changes. Duplication refers to the repetition of a segment on the chromosome. Deletion is the removal of a segment of a chromosome and the translocation is the transfer of a segment from one locus to another locus on the chromosome. Inversion is the insertion of a segment of chromosome in reverse order.

Question

Want to see the full answer?

Answer 1

Question

Chapter 15, Problem 15.4CR

Summary Introduction

To review: The fact that “inversions and reciprocal translocations are less lethal than aneuploidy, duplication, deletions and nonreciprocal translocation”.

Concept introduction: The aberration in chromosome structure and function can be caused due to aneuploidy, duplication, deletions and translocations. These can alter the chromosome to cause genetic disorders. Aneuploidy is a type of chromosomal alteration in which the number of chromosome changes. Duplication refers to the repetition of a segment on the chromosome. Deletion is the removal of a segment of a chromosome and the translocation is the transfer of a segment from one locus to another locus on the chromosome. Inversion is the insertion of a segment of chromosome in reverse order.

Expert Solution & Answer

Want to see the full answer?

Check out a sample textbook solution

See solution

Students have asked these similar questions

A sample of blood was taken from the above individual and prepared for haemoglobin analysis. However, when water was added the cells did not lyse and looked normal in size and shape. The technician suspected that they had may have made an error in the protocol – what is the most likely explanation? The cell membranes are more resistant than normal. An isotonic solution had been added instead of water. A solution of 0.1 M NaCl had been added instead of water. Not enough water had been added to the red blood cell pellet. The man had sickle-cell anaemia.

With reference to their absorption spectra of the oxy haemoglobin intact line) and deoxyhemoglobin (broken line) shown in Figure 2 below, how would you best explain the reason why there are differences in the major peaks of the spectra? Figure 2. SPECTRA OF OXYGENATED AND DEOXYGENATED HAEMOGLOBIN OBTAINED WITH THE RECORDING SPECTROPHOTOMETER 1.4 Abs < 0.8 06 0.4 400 420 440 460 480 500 520 540 560 580 600 nm 1. The difference in the spectra is due to a pH change in the deoxy-haemoglobin due to uptake of CO2- 2. There is more oxygen-carrying plasma in the oxy-haemoglobin sample. 3. The change in Mr due to oxygen binding causes the oxy haemoglobin to have a higher absorbance peak. 4. Oxy-haemoglobin is contaminated by carbaminohemoglobin, and therefore has a higher absorbance peak 5. Oxy-haemoglobin absorbs more light of blue wavelengths and less of red wavelengths than deoxy-haemoglobin