The fact that “inversions and reciprocal translocations are less lethal than aneuploidy, duplication, deletions and nonreciprocal translocation”. Concept introduction : The aberration in chromosome structure and function can be caused due to aneuploidy, duplication, deletions and translocations. These can alter the chromosome to cause genetic disorders. Aneuploidy is a type of chromosomal alteration in which the number of chromosome changes. Duplication refers to the repetition of a segment on the chromosome. Deletion is the removal of a segment of a chromosome and the translocation is the transfer of a segment from one locus to another locus on the chromosome. Inversion is the insertion of a segment of chromosome in reverse order.

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Chapter 15, Problem 15.4CR

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To review: The fact that “inversions and reciprocal translocations are less lethal than aneuploidy, duplication, deletions and nonreciprocal translocation”.

Concept introduction: The aberration in chromosome structure and function can be caused due to aneuploidy, duplication, deletions and translocations. These can alter the chromosome to cause genetic disorders. Aneuploidy is a type of chromosomal alteration in which the number of chromosome changes. Duplication refers to the repetition of a segment on the chromosome. Deletion is the removal of a segment of a chromosome and the translocation is the transfer of a segment from one locus to another locus on the chromosome. Inversion is the insertion of a segment of chromosome in reverse order.

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