PRESCOTT'S MICROBILOGY
PRESCOTT'S MICROBILOGY
11th Edition
ISBN: 9781264075515
Author: WILLEY
Publisher: MCG
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Chapter 14.5, Problem 2MI

MICRO INQUIRY For what other compounds would you also see this kind of diauxic growth?

Chapter 14.5, Problem 2MI, MICRO INQUIRY For what other compounds would you also see this kind of diauxic growth? Figure 14.16

Figure 14.16 Diauxic Growth. The diauxic growth curve of E. coli grown with a mixture of glucose and lactose. Glucose is first used, then lactose. A short lag in growth is present while the bacteria synthesize the enzymes needed for lactose use.

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a. What percentage of a drug is eliminated after 4 half-lives? Please round to the nearest percent.  b. What will happen to elimination of the drug in the previous question if the system is saturated? explain and show any math involved
If you wanted to reduce the difference between peak and trough levels that occur with repeated administration of a drug, how would you adjust the dose and dose interval without changing the plateau concentration (plateau is the average of peak and trough levels)? Select your answers for both dose and interval. Hint: It may be helpful to think about this problem using an example such as food. How would you eat if you wanted to maintain very steady hunger/satiety levels without changing your total caloric intake? Options: A. Dose; Increase dose     B. Dose; Decrease dose     C. Dose; Do not change dose     D. Interval; Increase the interval between doses (give the drug less frequently)    E. Interval; Decrease the interval between doses (give the drug more frequently)     F. Interval; Do not change the interval
What percentage of a drug is eliminated after 4 half-lives? Please round to the nearest percent. Show the math

Chapter 14 Solutions

PRESCOTT'S MICROBILOGY

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