1 SEM ACC W/RAVEN CARDED
12th Edition
ISBN: 9781265486297
Author: Raven
Publisher: MCGRAW-HILL HIGHER EDUCATION
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Textbook Question
Chapter 14, Problem 8A
When mutations that affected
a. elongation on the lagging but not the leading strand.
b. elongation on the leading but not the lagging strand.
c. initiation: cells complete replication but cannot start a new round.
d. the sliding clamp: loss makes the polymerase slower.
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Which of the following statements is TRUE
concerning the synthesis of the leading and
lagging strands of DNA in prokaryotic cells?
a.
O b.
The leading strand is synthesized by one
polymerase III continuously, and the lagging
strand is synthesized by several molecules of DNA
polymerase III.
d.
The leading and lagging strands are synthesized
at the same time by the one DNA polymerase I.
O c. The leading and lagging strands are synthesized
at the same time by the one DNA polymerase III.
The leading strand is synthesized by one
polymerase III, and the lagging strand is
synthesized by DNA polymerase I.
Match the enzymes provided from (1-4) in the list of choices with their matching function (A-D) during DNA replication.
A. Disrupts hydrogen bonds between DNA bases
B. Can only add nucleotides to an existing 3 OH end
C. Can't add nucleotides to a chain, but can make covalent bonds
D. Actually a specialized form of RNA polymerase
select
1. DNA polymerase
select
2. Primase
select
3. Ligase
select v 4. Helicase
A gene encoding one of the proteins involved in dna replication has been inactivated by a mutation in a cell. in the absence of this protein, the cell attempts to replicate its dna. What would happen during the dna replication process if each of the following proteins were missing?a. DNA polymerase B. DNA ligasec. Sliding clamp for DNA polymerased. nuclease that removes RNA primerse. DNA helicase F. primase
Chapter 14 Solutions
1 SEM ACC W/RAVEN CARDED
Ch. 14.1 - Describe the experiments of Griffith and Avery.Ch. 14.1 - Evaluate the evidence for DNA as genetic material.Ch. 14.2 - Explain how the WatsonCrick structure rationalized...Ch. 14.2 - Prob. 2LOCh. 14.3 - Prob. 1LOCh. 14.3 - Prob. 2LOCh. 14.4 - Prob. 1LOCh. 14.4 - Prob. 2LOCh. 14.4 - Diagram the functions found at the replication...Ch. 14.5 - Compare eukaryotic replication with prokaryotic.
Ch. 14.5 - Prob. 2LOCh. 14.5 - Prob. 3LOCh. 14.6 - Prob. 1LOCh. 14.6 - Prob. 2LOCh. 14 - Prob. 1DACh. 14 - Prob. 2DACh. 14 - Prob. 1IQCh. 14 - Prob. 2IQCh. 14 - How does the structure of eukaryotic genomes...Ch. 14 - Prob. 4IQCh. 14 - Prob. 1UCh. 14 - Which of the following is NOT a component of DNA?...Ch. 14 - Chargaff studied the composition of DNA from...Ch. 14 - The bonds that hold two complementary strands of...Ch. 14 - Prob. 5UCh. 14 - Prob. 6UCh. 14 - Which of the following is NOT pan of the...Ch. 14 - If one strand of a DNA is 5 ATCGTTAAGCGAGTCA 3,...Ch. 14 - Hershey and Chase used radioactive phosphorus and...Ch. 14 - The Meselson and Stahl experiment used a density...Ch. 14 - Prob. 4ACh. 14 - If the activity of DNA ligase was removed from...Ch. 14 - Successful DNA synthesis requires all of the...Ch. 14 - The synthesis of telomeres a. uses DNA polymerase,...Ch. 14 - When mutations that affected DNA replication were...Ch. 14 - Prob. 1SCh. 14 - In the Meselson-Stahl experiment, a control...Ch. 14 - Enzyme function is critically important for the...
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- Which of the following is the most accurate description of the E.coli replisome? a. Clamp loader positions two Pol III core polymerases on the leading strand and one Pol III core polymerase on the lagging strand b. Single strand template DNA forms two loops on the lagging strand while two Pol III core polymerases synthesize Okazaki fragments c. Okazaki fragments are synthesized in the opposite direction to movement of the replication fork d. Clamp loader only connects with Pol III core polymerases associated with the lagging strand e. Both b. and c. are accuratearrow_forwardDuring DNA replication, short RNA primers are made by the Primase. Why? a. To provide a 3'-OH so DNA polymerase can begin DNA synthesis. b. To recruit single stranded binding proteins to the correct location. c. To identify the termination sequence for DNA polymerase during DNA synthesis. d. To provide a 3'-OH so RNA polymerase can begin DNA synthesis. e. To identify the origin of replication to recruit the origin replication complex to the correct genomic location.arrow_forwardWhich of the following statements is FALSE regarding the molecular mechanism for DNA polymerases? A. The active site contains 2 divalent metal ions B. A single stranded DNA template is required C. The enzyme can only attach a new deoxynucleotide to the 5’ end of a growing chain D. The 3’OH on the deoyxyribose ring attacks a phosphate of a dNTP to produce a new phosophodiester bond E. None of the above (all are true statements)arrow_forward
- A diagram of a prokaryotic replication fork is shown. As in class, RNA primers are represented by a wavy line and DNA represented by a straight line. From the list below pick all the statements that are TRUE of this replication fork. (Multiple answers possible) A.Primer sequences are not correct. B. DNA being synthesized is not complementary and antiparallel to the template. C. Direction of DNA synthesis is not correct (not 5' to 3'). D. At least one protein in the diagram is mislabeled.arrow_forwardWhich of the following types of DNA damage would be hardest to repair using the DNA repair pathways?A. Complete removal of three nucleotides in the middle of one strand.B. A covalent bond between a base on one strand and a base on the complementary strand.C. Incorporation of a sugar other than deoxyribose into one strand.D. Covalent attachment of a short polypeptide to a single base.E. A covalent bond between a base and a deoxyribose on the same strand. Please explain why it's Barrow_forwardDuring DNA replication, the leading strand is synthesized continuously, while the lagging strand is synthesized as Okazaki fragments. This is because: O A. DNA polymerases can bind to only one strand at a time. O B. Two different DNA polymerases are involved in replication (DNA polymerase I and II). O C. DNA synthesis can take place only in the 5 -> 3 direction. D. The primers are made of RNA. Reset Selection Previous NEXT Save Exit MacBook Pro Q Search or enter website name & %24 %23 4 3 00 < COarrow_forward
- Which statement below is true? Select one: a. Okazaki fragments are produced in eukaryotic DNA replication but not in prokaryotic DNA replication. b. In both eukaryotes and prokaryotes, the template strand of DNA is read in the template’s 3’ to 5’ direction, while the new strand DNA is synthesized in new strand’s 5’ to 3’ direction. c. In eukaryotes, synthesis of the new DNA strand is from 5’ to 3’, whereas in prokaryotes it is random. d. In eukaryotes, synthesis of the new DNA strand is from 5’ to 3’, whereas in prokaryotes it is from 3’ to 5’. e. In eukaryotes, synthesis of the new DNA strand is from 3’ to 5’, whereas in prokaryotes it is from 5’ to 3’.arrow_forwardIn observing replication of prokaryotic plasmids by electron microscopy, it is apparent that: a. replication is initiated at two distinct origins of replication. b. the template strands completely unwind before replication begins. c. replication initiates from a single origin, creating a replication bubble d. the plasmid is linearized prior to replicationarrow_forwardWhich of the following statements about the DNA replication is false? a. Synthesis of the new DNA strands is form 39 to 59 b.Synthesis of the new DNA strands is from 59 to 39 c. DNA Unwinds, primase adds RNA primer, DNA polymerases synthesize the new strand and remove the RNA primer d. Many initiation points exist in each eukaryotic chromosome. e. Okazaki fragments are synthesized in the opposite direction from the direction in which the replication for moves.arrow_forward
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