Biology
Biology
12th Edition
ISBN: 9780134813448
Author: Audesirk, Teresa, Gerald, Byers, Bruce E.
Publisher: Pearson,
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Chapter 14, Problem 5RQ
Summary Introduction

To describe: The working mechanism of CRISPR-Cas9 tool.

Introduction: Clustered Regularly Interspaced Short Palindromic Repeats (CRISPR) is a powerful biotechnology for editing genomes. They occur in all archaeal genomes and are distributed widely in repeated sequences of prokaryotes.

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The metabolic pathway below is used for the production of the purine nucleotides adenosine monophosphate (AMP) and guanosine monophosphate (GMP) in eukaryotic cells. Assume each arrow represents a reaction catalyzed by a different enzyme. Using the principles of feedback inhibition, propose a regulatory scheme for this pathway that ensures an adequate supply of both AMP and GMP, and prevents the buildup of Intermediates A through G when supplies of both AMP and GMP are adequate.
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examples of synamptomorphy

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